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Record W4415175526 · doi:10.1007/s00467-025-06960-6

Establishing core outcomes and minimal clinically important differences for childhood steroid sensitive nephrotic syndrome clinical trials: results from a Delphi consensus process

2025· article· en· W4415175526 on OpenAlexaff
Cal Robinson, Simon Carter, Nowrin Aman, Valentina Bruno, Brian H. Cuthbertson, Mackenzie Garner, Eddy Fan, Christoph Licht, Ashlene McKay, Seetha Radhakrishnan, Véronique Rowley, Chia Wei Teoh, Jovanka Vasilevska‐Ristovska, Anna Heath, Rulan S. Parekh

Bibliographic record

VenuePediatric Nephrology · 2025
Typearticle
Languageen
FieldMedicine
TopicRenal Diseases and Glomerulopathies
Canadian institutionsWomen's College HospitalHealth Sciences CentrePublic Health OntarioHospital for Sick ChildrenSunnybrook Health Science CentreInstitute for Clinical Evaluative SciencesSickKids FoundationUniversity of Toronto
Fundersnot available
KeywordsNephrotic syndromeDelphi methodNephrologyMinimal change diseaseCore (optical fiber)MEDLINEClinical trial

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.694
metaresearch head score (Gemma)0.672
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.694
Threshold uncertainty score0.377

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.6940.672
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0050.008
Bibliometrics0.0050.005
Science and technology studies0.0050.004
Scholarly communication0.0090.006
Open science0.0050.016
Research integrity0.0050.009
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.397
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractno

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