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Record W4415223304 · doi:10.1371/journal.pone.0334524

Care professionals’ accounts of providing support and treatment for people with co-occurring alcohol use disorder and depression in the North East of England, UK: A qualitative study informed by complexity theory

2025· article· en· W4415223304 on OpenAlexaboutno aff
Amy O’Donnell, Eileen Kaner, Barbara Hanratty, Éilish Gilvarry, Sarah Wigham, Katherine Jackson

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicSubstance Abuse Treatment and Outcomes
Canadian institutionsnot available
FundersNational Institute for Health and Care Research
KeywordsQualitative researchNorth eastDepression (economics)Mental healthSubstance useNova scotiaInvestment (military)Alcohol use disorderMajor depressive disorder

Abstract

fetched live from OpenAlex

INTRODUCTION: There is an acknowledged care gap for patients with co-occurring substance use and mental ill-health. This study sought to use complexity theory to help make sense of the experiences of people who deliver or commission formal care for patients with alcohol use disorder and depression across one specific health and social care system. METHOD: Qualitative interviews with 26 health and social care professionals in the North East and North Cumbria Integrated Care System, England, were conducted. Data analysis was undertaken using reflexive thematic analysis and informed by key concepts from complexity theory. RESULTS: Three main themes were identified: (1) how the interplay between risk, stigma and resource pressures influences how care professionals interpret and apply practice guidelines; (2) how individualised and disjointed practices have structural and historical roots, in particular the impact of health service commissioning cycles; (3) ways in which practitioners have been able to adapt and engage in creative practice to temporarily plug gaps in care. CONCLUSIONS: The pressure of working with increasingly scarce resources, within a highly fragmented, shifting, and risk-averse care infrastructure, adversely affected professionals' capacity to provide consistent, patient-centered support. Innovations have emerged that address some of these barriers, but further investment is needed to better support the substance use and mental health workforce, including lived experience peer workers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.026
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.070

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.026
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0100.013
Scholarly communication0.0050.005
Open science0.0020.008
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.366
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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