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Record W4415259064 · doi:10.22178/pos.122-7

A Study on the Screening for Lactic Acid Bacteria from Fura Da Nono with Antibacterial and Bio Preservative Properties

2025· article· en· W4415259064 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenuePath of Science · 2025
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacological Effects of Natural Compounds
Canadian institutionsAlberta Health Services
Fundersnot available
KeywordsBacteriocinPreservativeLactobacillus plantarumLactic acidNisinBacteriaAntibacterial activityBiopreservationLactobacillus caseiShelf life

Abstract

fetched live from OpenAlex

The study explores the isolation and screening of lactic acid bacteria (LAB) from the traditional Nigerian fermented beverage fura da nono with a focus on their antibacterial and biopreservative properties. A total of fifty LAB strains were isolated using selective MRS agar, and presumptive identification was achieved via phenotypic characterisation. Four isolates displaying prominent antibacterial activity were further identified through 16S rRNA gene sequencing, revealing Lactobacillus plantarum FJ390111, Lactobacillus casei CP14326, and Enterococcus lactis NR117562, with an additional isolate, Lysinibacillus fusiformis, identified as an environmental contaminant. Crude bacteriocin extracts, obtained via ammonium sulfate precipitation and dialysis, were evaluated against foodborne pathogens, including Staphylococcus aureus, Salmonella typhi, and Escherichia coli using agar diffusion assays. The LAB bacteriocins demonstrated optimal inhibitory activity at pH 6 and 35 °C, whereas significant declines in activity were noted at temperatures above 40 °C and during extended storage (96 hours at 37 °C). Graphical data and tables confirm that the bacteriocin extracts produced zones of inhibition ranging from approximately 11 to 15 mm under optimal conditions, with Enterococcus lactis showing particularly moderate to high activity. These results underscore the potential application of LAB-derived bacteriocins as natural bio-preservatives in the food industry. However, the heat sensitivity and degradation over time highlight the need for further formulation improvements. The study concludes that with enhanced stabilisation and rigorous quality control, bacteriocins from traditional LAB can serve as effective alternatives to chemical preservatives in ensuring food safety and extending product shelf life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.217
Threshold uncertainty score0.619

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.219
GPT teacher head0.442
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it