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Record W4415265263 · doi:10.1111/ped.70198

Midterm comprehensive cardiovascular assessment of patients with Kawasaki disease

2025· article· en· W4415265263 on OpenAlexafffund
L. C. T. Capovilla, Rocío Gutiérrez, Fabiola Breault, Youcef Bouzidi, Geneviève Mailhot, Daniel Curnier, Nagib Dahdah

Bibliographic record

VenuePediatrics International · 2025
Typearticle
Languageen
FieldMedicine
TopicKawasaki Disease and Coronary Complications
Canadian institutionsUniversité de MontréalMontreal Clinical Research InstituteCentre Hospitalier Universitaire Sainte-Justine
FundersCHU Sainte-Justine Foundation
KeywordsKawasaki diseaseDiseaseSocioeconomic statusMEDLINERisk assessment

Abstract

fetched live from OpenAlex

BACKGROUND: Kawasaki disease (KD) causes coronary artery aneurysms (CAA), which require healthy lifestyle prevention. METHODS: We conducted a cross-sectional study examining anthropometric measurements, biochemical data, nutrient intake, and physical activity profile in a cohort of KD patients with CAA (KD-A) or without CAA (KD-N). Age-adjusted anthropometric measurements, biochemical markers from blood tests, 3-month food frequency, and standardized physical activity habits were collected 5-10 years after KD. RESULTS: This included 9 KD-A patients, 39 KD-N patients, and 27 controls (CTL). The prevalence of overweight or obesity was significantly higher in KD-A patients compared to KD-N and to CTL (respectively 33.3% and 22.2%, versus 15.5% and 20.5%, compared to 7.0% and 7.0% in CTL; p = 0.002). KD-A patients had higher CRP compared to KD-N (1.34 ± 1.29 mg/L vs. 0.65 ± 0.91 mg/L; p = 0.047), compared to CTL (0.68 ± 1.11 mg/L). KD-A and KD-N, respectively, consume an excess of total lipids in 22% and 42%, an excess of saturated fatty acids in 67% and 84%, and an excess of total sugars in 67% and 61%. KD-A spend less than 30 min a day doing physical activity compared to KD-N in 62% and 22%, respectively, and only 13% of KD-A but 45% of KD-N spend more than 60 min a day on physical activity. CONCLUSION: A deviation from a healthy lifestyle is present in KD patients 5-10 years following their diagnosis and treatment, making them susceptible to developing significant cardiac complications. Hence, the importance of implementing healthy lifestyle guidelines, adapting those to the socioeconomic context, with specific recommendations regarding the cardiovascular risks of these young patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.368

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.294
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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