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Record W4415265629 · doi:10.1017/cjn.2025.10448

Discharge Site Is Associated With Long-Term Functional Outcomes in Patients With Ruptured Intracranial Aneurysms

2025· article· en· W4415265629 on OpenAlexaffvenue
Diego A. Ortega-Moreno, Ibrahim Almulhim, Jerry C. Ku, Nicole M Cancelliere, Danilo B. Diestro, Thomas R. Marotta, Julian Spears, Adam A. Dmytriw, Vitor Mendes-Pereira

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2025
Typearticle
Languageen
FieldMedicine
TopicIntracranial Aneurysms: Treatment and Complications
Canadian institutionsToronto Metropolitan UniversityUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsRehabilitationHospital dischargeAneurysmRetrospective cohort studyAcute care

Abstract

fetched live from OpenAlex

ABSTRACT Objective: To evaluate the impact of discharge destination on long-term functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) and its association with achieving functional independence. Methods: This retrospective cohort study included patients with aSAH treated endovascularly at a tertiary neurovascular center between October 2019 and November 2024. Patients who died before hospital discharge were excluded. Group comparisons were performed using one-way analysis of variance, Kruskal–Wallis, paired-sample t-tests and Pearson’s χ 2 . Multivariable logistic regression was used to assess the association between discharge site and functional independence achievement, adjusting for age, sex, World Federation of Neurosurgical Societies (WFNS) grade and modified Rankin Scale (mRS) score at discharge. Results: A total of 213 patients (mean age 55.9 ± 13.7 years; 77% female) were included. Hypertension (57.7%) and previous smoking (45.1%) were the most common risk factors. Significant differences in age, sex, WFNS grade and modified Fisher Scale scores were observed across discharge groups. While patients discharged home had better overall outcomes, those with poor WFNS grades showed greater reductions in mRS at 6 and 12 months when discharged to an acute rehabilitation center. Regression analysis demonstrated that discharge to an acute rehabilitation center was independently associated with higher odds of functional independence, while discharge to a primary care hospital decreased these odds. Conclusion: Discharge to a primary care hospital after aSAH was associated with worse long-term outcomes. In contrast, early transfer to an acute rehabilitation center significantly improved functional independence, particularly among patients with poor baseline neurological status.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.247
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques→Same topicIntracranial Aneurysms: Treatment and Complications→French-language works237,207→