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Tracking the Evolving Role of Artificial Intelligence in Implementation Science: Protocol for a Living Scoping Review of Applications, Evaluation Approaches and Outcomes

2025· preprint· en· W4415283583 on OpenAlexaff
Guillaume Fontaine, Olivia Di Lalla, Susan Michie, Byron J. Powell, Vivian Welch, James Thomas, J. Chan, Samira Abbasgholizadeh Rahimi, France Légaré, Janna Hastings, Sylvie Lambert, Justin Presseau, Sharon E. Straus, Ian D. Graham, Ruopeng An, Elakpa Daniel Ngbede, Meagan Mooney, Alenda Dwiadila Matra Putra, Rachael Laritz, Natalie Taylor

Bibliographic record

VenueF1000Research · 2025
Typepreprint
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsInstitute for Work & HealthUniversity of TorontoSt Mary's Hospital CentreUniversité LavalMcGill UniversityUniversity of OttawaMcGill University Health CentreBruyèreCentre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-MontréalMila - Quebec Artificial Intelligence InstituteOttawa Public HealthSt. Michael's HospitalJewish General HospitalOttawa Hospital
Fundersnot available
KeywordsGrey literatureSystematic reviewProtocol (science)Field (mathematics)PreprintApplications of artificial intelligenceTracking (education)Sustainability

Abstract

fetched live from OpenAlex

Background Artificial intelligence (AI) offers significant opportunities to improve the field of implementation science by supporting key activities such as evidence synthesis, contextual analysis, and decision-making to promote the adoption and sustainability of evidence-based practices. This living scoping review aims to: (1) map applications of AI in implementation research and practice; (2) identify evaluation approaches, reported outcomes, and potential risks; and (3) synthesize reported research gaps and opportunities for advancing the use of AI in implementation science. Methods This scoping review will follow the Joanna Briggs Institute (JBI) methodology and the Cochrane guidance for living systematic reviews. A living scoping review is warranted to keep up with the rapid changes in AI and its growing use in implementation science. We will include empirical studies, systematic reviews, grey literature, and policy documents that describe or evaluate applications of AI to support implementation science across the steps of the Knowledge-to-Action (KTA) Model. AI methods and models of interest include machine learning, deep learning, natural language processing, large language models, and related technologies and approaches. A search strategy will be applied to bibliographic databases (MEDLINE, Embase, CINAHL, PsycINFO, IEEE Xplore, Web of Science), relevant journals, conference proceedings, and preprint servers. Two reviewers will independently screen studies and extract data on AI characteristics, specific implementation task according to the KTA Model, evaluation methods, outcome domains, risks, and research gaps. Extracted data will be analyzed descriptively and synthesized narratively using a mapping approach aligned with the KTA Model. Discussion This living review will consolidate the evidence base on how AI is applied across the spectrum of implementation science. It will inform researchers, policymakers, and practitioners seeking to harness AI to improve the adoption, scale-up, and sustainability of evidence-based interventions, while identifying areas for methodological advancement and risk mitigation. Review registration Open Science Framework, May 2025: https://doi.org/10.17605/OSF.IO/2Q5DV

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.245
metaresearch head score (Gemma)0.294
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.755
Threshold uncertainty score0.931

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2450.294
Meta-epidemiology (narrow)0.0060.007
Meta-epidemiology (broad)0.0140.018
Bibliometrics0.0160.018
Science and technology studies0.0080.009
Scholarly communication0.0110.015
Open science0.0060.010
Research integrity0.0170.012
Insufficient payload (model declined to judge)0.0820.023

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.738
GPT teacher head0.636
Teacher spread0.102 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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