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Record W4415304696 · doi:10.21203/rs.3.rs-7872114/v1

Co-occurring mood, anxiety, and substance use disorders in Canada 2022: Prevalence, patterns, correlates, and changes over time

2025· preprint· W4415304696 on OpenAlexafffundabout
Jillian Halladay, Chris Ji, Katholiki Georgiades, Tim Slade, Cath Chapman, Matthew Sunderland, James MacKillop

Bibliographic record

VenueResearch Square · 2025
Typepreprint
Language
FieldPsychology
TopicMental Health Treatment and Access
Canadian institutionsMcMaster University
FundersNational Health and Medical Research CouncilMedical Research CouncilCanadian Institutes of Health ResearchMcMaster University
KeywordsAnxietyMental healthMood disordersPrevalence of mental disordersMoodOddsDepression (economics)Substance abuseOdds ratio

Abstract

fetched live from OpenAlex

Abstract Objective: This study examines: (1) the 2022 prevalence and co-occurrence of past 12 month mood, anxiety, and substance use disorders (SUD)among Canadian’s aged 15+; and (2) changes in the prevalence of co-occurring disorders from 2012 to 2022. Methods: Data from the 2022 Mental Health and Access to Care Survey (MHACS; n=9,861) and the 2012 Canadian Community Health Survey’s Mental Health Component (CCHS-MH; n=25,113) were analyzed. Diagnoses for past 12 month mood (major depressive episode, bipolar), anxiety (generalized anxiety, social phobia), and substance use (alcohol, cannabis, and drug) disorders were assessed using the World Health Organization Composite International Diagnostic Interview. Multivariable multinomial regression examined demographic and clinical correlates, as well as changes over time, of mood/anxiety disorder(s) alone, SUD(s) alone, and concurrent disorders (mood/anxiety+SUD). Age (youth aged 15-24 vs adults 26+) and sex (females vs males) differences were explored through stratified analyses and interactions. Results: In 2022, 16.4% of Canadians met criteria for a mood (8.4%), anxiety (9.9%), or SUD (3.5%). Of those with at least one disorder, co-occurrence was common: 39.5% had 2+ disorders with 10.6% experiencing concurrent SUD and mood/anxiety disorders. Among those with an SUD, 48.9% had a concurrent mood/anxiety disorder, while 15.2% and 9.6% of those with a mood and anxiety disorders respectively had a concurrent SUD. Youth, unemployed individuals, and those with high distress or suicidality had elevated odds of concurrent disorders. Males had higher overall concurrent disorder prevalences, but among those with SUDs, concurrent disorders were higher among females. While the odds of SUD-alone declined, mood/anxiety disorders and concurrent disorders doubled from 2012 to 2022. Conclusions: Findings highlight the urgent need for integrated mental health and substance use services in Canada, particularly for youth and females, who are disproportionately affected.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.152

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.007
Science and technology studies0.0020.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.396
Teacher spread0.354 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractno

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