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Record W4415322104 · doi:10.1007/s40471-025-00374-6

Transporting: What Is It and How Do You Do It?

2025· article· en· W4415322104 on OpenAlex
Michael Webster‐Clark, Alexander Breskin, Emilie D. Duchesneau, Kara E. Rudolph

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCurrent Epidemiology Reports · 2025
Typearticle
Languageen
FieldMathematics
TopicAdvanced Causal Inference Techniques
Canadian institutionsMcGill University
FundersNational Institute on Drug AbuseWake Forest University
KeywordsGeneralizability theoryExternal validityEstimatorPopulationInternal validityField (mathematics)

Abstract

fetched live from OpenAlex

Purpose of Review: Transportability, one of the twin faces of external validity (alongside generalizability), refers to the ability to use effect estimates in a study population to understand effects in a different population. In this review, we aimed to provide an overview of ongoing methodological developments in the field of transportability and provide a tutorial walking through key steps in the transportability process. Recent Findings: We cover recent work done to distinguish the concept of transportability from generalizability (or external validity more broadly), define core conditions necessary for transporting treatment effects to a different target population, outline approaches to identify sufficient adjustment sets, and design estimators to estimate transported treatment effects. We then illustrate the application of these methods through a case study comparing the effects of two adjuvant chemotherapies for breast cancer in patients within the National Cancer Database, a large national cancer registry, using effect estimates transported from a randomized controlled trial. Summary: While external validity, generalizability, and transportability have long been recognized as important elements of epidemiology, they have historically been treated interchangeably and discussed qualitatively in discussion sections of manuscripts. Over the past two decades, however, major strides have been made to formally define these concepts and introduce analytic methods for them that are valid under well-defined conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.669
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.273
GPT teacher head0.492
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it