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Record W4415348964 · doi:10.1101/2025.10.15.25337958

Should we screen less frequently for chlamydia and gonorrhoea in gay and bisexual men who have sex with men? Findings from a global crowdsourcing exercise with experts

2025· preprint· en· W4415348964 on OpenAlexafffund
Teralynn Ludwick, Ethan T Cardwell, Tin D. Vo, Lauren Ware, Phoebe Quinn, Eric P. F. Chow, Daniel Grace, Jane S. Hocking, Fabian Yuh Shiong Kong

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldPsychology
TopicSexuality, Behavior, and Technology
Canadian institutionsPublic Health OntarioUniversity of Toronto
FundersNational Health and Medical Research CouncilCanadian Institutes of Health ResearchUniversity of Toronto
KeywordsAsymptomaticMen who have sex with menPopulationReproductive healthChlamydiaCrowdsourcingDemographicsPublic health

Abstract

fetched live from OpenAlex

OBJECTIVES: Many countries recommend 3-monthly chlamydia/gonorrhoea screening for gay, bisexual and other men who have sex with men (GBMSM). Evidence about the limited impact of frequent, asymptomatic gonorrhoea/chlamydia screening on population prevalence, coupled with concerns about overburdened health services and antimicrobial resistance (from frequent treatment), calls into question current approaches to asymptomatic screening. We explored sexual health professionals/experts' arguments in favour/against reducing asymptomatic screening using Polis (www.Pol.is), an online, crowdsourcing tool for understanding what large groups think. METHODS: Recruited via global peak bodies/networks, 99 individuals in the field of sexually transmitted infections (STIs) (43.4 % clinicians, 35.4% researchers) primarily from Australasia (41.4%), UK/Europe (29.3%) and North America (22.2%) participated. Ninety-one statements were submitted in favour/against reduced screening for GBMSM (eg, 'Bisexual men who don't test regularly risk putting women at risk'). Participants voted on submitted statements (agree/disagree/pass). Statements with ≥80% agreement were considered as 'strong' support, 70%-79% 'moderate' and ≤69% 'mixed'. Statements were grouped using content analysis to assess support for clusters of related statements. RESULTS: There was 'mixed support' for statements on: (1) the impact of screening in reducing prevalence; (2) whether asymptomatic infections pose clinical harm/necessitate treatment; and (3) risk of antimicrobial resistance. Statements advocating for 6-monthly screening received 'moderate support', with arguments centring on resource use. Participants 'strongly supported' the need for community engagement and maintaining frequent HIV/syphilis screening. CONCLUSIONS: While there were mixed opinions about relative utility, risks and harms of reducing chlamydia/gonorrhoea screening for GBMSM, arguments relating to resource constraints may provide common ground for policy changes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.058
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.028
Threshold uncertainty score0.097

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.058
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0030.003
Scholarly communication0.0020.002
Open science0.0010.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.352
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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