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Record W4415356833 · doi:10.1097/xce.0000000000000347

Composite risk of cardiovascular disease comorbidity in people living with diabetes in Africa.

2025· article· en· W4415356833 on OpenAlexaff
Regina Idu Ejemot-Nwadiaro, Divine-Favour Chichenim Ofili, Stephen Chukwuma Ogbodo, Henshaw Uchechi Okoroiwu, Ugochinyere Vivian Ukah

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsJewish General HospitalMcGill University
Fundersnot available
KeywordsDiabetes mellitusComorbidityDiseaseType 2 diabetesRisk factorRisk assessmentEpidemiology

Abstract

fetched live from OpenAlex

Aim: Despite the high likelihood of comorbidity from shared risk factors, the cardiovascular disease (CVD) risk, based on the combined presence of key risk factors, in people with diabetes mellitus is poorly understood. Thus, this study quantifies the composite CVD risk and its association with sociodemographic factors in people living with diabetes mellitus in Africa. Methods: Using the WHO STEPwise approach to noncommunicable diseases risk factor Surveillance (STEPS) data and generalized linear mixed models, we analyzed CVD risk in 4738 nonpregnant adults with diabetes in Africa. The composite CVD risk was measured with the STEPS-CARDIO index, which includes smoking, overweight/obesity, hypertension, physical activity, and diet. Results: The mean STEPS-CARDIO score ranged from 2 to 3.22, signifying that, on average, people with diabetes in the included countries had a medium risk of developing CVD. Higher CVD risk was observed with increasing age [odds ratio (OR): 1.03, 95% confidence interval (CI): 1.02-1.04], and among women compared with men (OR: 1.20, 95% CI: 1.05-1.38). Other factors - education, marital status, occupation, and household size - were also generally associated with elevated CVD risk, but being a student (compared to being employed) was associated with lower risk (OR: 0.51, 95% CI: 0.31-0.86). Additional analyses suggested that this protective association was partly age-driven, as most students were younger than 30 years. Conclusion: Findings highlight gendered and social differences in CVD risk among people with diabetes mellitus in Africa, underscoring the need for tailored preventive interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.194
Teacher spread0.184 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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