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Record W4415364194 · doi:10.1503/cmaj.250237

Recommendation on screening adults for depression using a screening tool

2025· review· en· W4415364194 on OpenAlexafffundvenueabout
Eddy Lang, Casey Gray, John C. LeBlanc, Heather Colquhoun, Gregory Traversy

Bibliographic record

VenueCanadian Medical Association Journal · 2025
Typereview
Languageen
FieldPsychology
TopicMental Health Treatment and Access
Canadian institutionsUniversity of TorontoPublic Health Agency of CanadaUniversity of CalgaryDalhousie UniversityAlberta Health Services
FundersAgency for Healthcare Research and QualityMinistry of Health, British ColumbiaDalhousie UniversityMental Health CommissionUniversity of AlbertaU.S. Department of Health and Human ServicesUniversity of OttawaPublic Health Agency of CanadaMcGill UniversityJewish General HospitalPublic Health AgencyMcMaster University
KeywordsDepression (economics)Ask priceMEDLINEPrimary careHealth screeningMedical screening

Abstract

fetched live from OpenAlex

BACKGROUND: Depression negatively affects how a person feels, thinks, or behaves; is associated with impaired functioning in social and work settings; and can be associated with thoughts of suicide. This update of the 2013 Canadian Task Force on Preventive Health Care guideline provides an evidence-based recommendation about instrument-based screening for depression. METHODS: For this update, we commissioned a systematic review on benefits and harms of instrument-based screening (i.e., using a screening tool) for depression among adults. The systematic review covered relevant literature from October 2018 to May 2020, updated to January 2025 for trials, and to March 2025 for trial registries. We examined patient values and preferences via patient engagement surveys and focus groups; we engaged content experts and other interest holders at key points throughout the project. We used the Grading of Recommendations, Assessment, Development and Evaluation approach to determine the certainty of evidence for each outcome and strength of the recommendation; adhered to the Guidelines International Network principles of managing competing interests; and followed Appraisal of Guidelines for Research and Evaluation, and Guidance for Reporting Involvement of Patients and the Public reporting guidance. RECOMMENDATIONS: We recommend against screening all adults aged 18 years and older for depression using questionnaires (strong recommendation, very low-certainty evidence), based on evidence suggesting that depression screening using a screening tool has little to no effect on health. This recommendation does not apply to adults with a personal history, current diagnosis, or clinical suspicion of a diagnosis of depression or another mental health disorder. It does apply to those who may be at an elevated risk of depression. INTERPRETATION: The recommendation against screening adults for depression using a screening tool emphasizes the importance of good clinical care, where clinicians ask about their patients' well-being and remain vigilant for symptoms and signs of depression.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.040
metaresearch head score (Gemma)0.235
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.040
Threshold uncertainty score0.210

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0400.235
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0070.020
Bibliometrics0.0070.006
Science and technology studies0.0020.003
Scholarly communication0.0070.008
Open science0.0120.005
Research integrity0.0230.014
Insufficient payload (model declined to judge)0.0340.020

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.434
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes4
Has abstractyes

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