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Record W4415386246 · doi:10.21037/acr-25-8

Transient unilateral oculomotor and trigeminal nerve palsy following intranasal local anesthetic infiltration: a case report

2025· article· en· W4415386246 on OpenAlexaff
Samuel Tholl, Juan Carlos Hernaiz‐Leonardo, Richmond Quan Qing Lim, Azin Tabari, Amin R. Javer

Bibliographic record

VenueAME Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicFacial Rejuvenation and Surgery Techniques
Canadian institutionsSt. Paul's HospitalUniversity of British Columbia
Fundersnot available
KeywordsLocal anestheticLocal anesthesiaOculomotor nerve palsyTrigeminal nerveAnestheticNasal administrationInfiltration (HVAC)

Abstract

fetched live from OpenAlex

Background: Complications from in-office inferior turbinate (IT) and septal swell body coblation typically include pain, congestion, and bleeding. However, rare cases of cranial nerve palsies from local anesthetic infiltration can occur. We present a rare case of an oculomotor nerve palsy and palsies of the ophthalmic (V1) and maxillary (V2) branches of the trigeminal nerve following intranasal local anesthetic infiltration prior to coblation, a complication not previously documented in the literature. Awareness of such rare and transient complications can help surgeons and clinicians avoid unnecessary interventions and better counsel patients. Case Description: A 75-year-old female with a one-year history of recalcitrant bilateral nasal obstruction underwent an in-office primary bilateral coblation of the ITs and septal swell bodies. Four percent lidocaine-soaked neuropatties were applied over the ITs and septal swell bodies, followed by infiltration with 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine. Shortly after infiltration, the patient developed left-sided ptosis and was unable to adduct the left eye, causing diplopia. Additionally, the patient reported paresthesia in the V1 and V2 dermatomes. All symptoms resolved within 15 minutes. At the 6-week post-procedure visit, there was no sustained diplopia, left eye ptosis, or facial paresthesia. These symptoms also remained absent at the six-month post-procedure visit. Conclusions: Although relatively low-risk, surgeons should be aware of potential cranial nerve complications associated with intranasal anesthetic administration. Recognizing the benign and reversible nature of such presentations may help avoid unnecessary diagnostic workups, reduce patient distress, and reinforce best practices such as aspiration prior to infiltration and slow injection techniques.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.002
Science and technology studies0.0030.002
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0050.003
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.292
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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