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Record W4415388687 · doi:10.5646/ch.2025.31.e35

Effects of aerobic and inspiratory strength muscle training on exaggerated blood pressure response during exercise in hypertensive patients

2025· article· en· W4415388687 on OpenAlexaff
Ho Jeong Min, Hyun Jeong Kim, Setor K. Kunutsor, Sae Young Jae

Bibliographic record

VenueClinical Hypertension · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsUniversity of Manitoba
FundersMinistry of Science and ICT, South KoreaNational Research Foundation of KoreaNational Research FoundationKorean Society of Hypertension
KeywordsBlood pressureAerobic exerciseAnaerobic exerciseStrength trainingHemodynamicsBicycle ergometerAngiologyDiastole

Abstract

fetched live from OpenAlex

Background: An exaggerated blood pressure response (EBPR) to exercise predicts future hypertension and cardiovascular disease.Although aerobic exercise (AE) and inspiratory muscle strength training (IMST) lower resting blood pressure (BP), their capacity to attenuate EBPR has not been compared.This study examined the effects of AE and IMST on EBPR during maximal exercise testing in hypertensive patients.Methods: Twenty-four participants were randomly assigned to AE (n = 12, 40-70% of heart rate reserve, 30 minutes) or IMST (n = 12, 55-75% of maximal inspiratory pressure, 30 breaths/day), 5 days/week for 8 weeks.Brachial BP and heart rate were measured at rest, during each stage of a graded cycle-ergometer test, and during recovery.EBPR was defined as peak systolic BP (SBP) 210 mmHg (men) or 190 mmHg (women).Primary outcomes were changes in SBP across exercise stages and prevalence of EBPR.Results: Both interventions reduced resting SBP (-8.0 mmHg) and diastolic BP (-4.2 mmHg).The prevalence of EBPR declined from 62.5% to 45.8%, though this did not reach statistical significance ( 2 = 1.34,P = 0.25).Subgroup analysis showed greater SBP attenuation at moderate intensity with AE (-9.2 mmHg, P = 0.020) and at higher intensity with IMST (-8.8 mmHg, P = 0.042).Conclusions: Both AE and IMST attenuated SBP responses during submaximal exercise in hypertensive individuals.These findings highlight a potential for exercise training to mitigate EBPR in hypertension.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.939
Threshold uncertainty score0.678

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.274
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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