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Record W4415423726 · doi:10.1016/j.lana.2025.101286

Retraction notice to Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: the TOGETHER randomized platform clinical trial [The Lancet Regional Health–Americas Volume 6, February 2022, 100142]

2025· article· en· W4415423726 on OpenAlexaff
Gilmar Reis, Eduardo Augusto Dos Santos Moreira Silv, Daniela Carla Medeiros Silv, Lehana Thabane, Aline Cruz Milagres, Thiago Santiago Ferreir, Castilho Vitor Quirino dos Santos, Adhemar Dias de Figueiredo Neto, Eduardo Diniz Callegari, Leonardo Cançado Monteiro Savassi, Maria Izabel Campos Simplicio, Luciene Barra Ribeiro, Rosemary Oliveira, Ofir Harari, Holly Bailey, Jamie I. Forrest, А. В. Глущенко, Sheila Sprague, Paula McKay, Craig R. Rayner, Hinda Ruton, Gordon Guyatt, Edward J. Mills

Bibliographic record

VenueThe Lancet Regional Health - Americas · 2025
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 Clinical Research Studies
Canadian institutionsMcMaster UniversityImpact
Fundersnot available
KeywordsNoticeMetforminClinical trialVolume (thermodynamics)Standard of careRandomized controlled trial

Abstract

fetched live from OpenAlex

[This retracts the article DOI: 10.1016/j.lana.2021.100142.].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaResearch integrity
Domain: not available · Genre: Other
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
gptResearch integrity
Domain: not available · Genre: Editorial
About the Canadian research system: no · About a Canadian topic: no
Not applicablehigh
models agreeAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.336
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.094
GPT teacher head0.475
Teacher spread0.381 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

Study designNot applicable
Domainnot available
GenreOther · Editorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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