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Record W4415431826 · doi:10.1021/acs.jctc.5c01333

Capturing Electron Correlation with Machine Learning through a Data-Driven CASPT2 Framework

2025· article· en· W4415431826 on OpenAlexaff
Grier M. Jones, Konstantinos D. Vogiatzis

Bibliographic record

VenueJournal of Chemical Theory and Computation · 2025
Typearticle
Languageen
FieldMaterials Science
TopicMachine Learning in Materials Science
Canadian institutionsDairy Farmers of OntarioUniversity of Toronto
FundersDivision of Chemistry
KeywordsElectronic correlationCorrelationPerturbation (astronomy)Complete active spacePerturbation theory (quantum mechanics)Set (abstract data type)Space (punctuation)Parameter space

Abstract

fetched live from OpenAlex

Multireference perturbation theory methods, such as complete active space second-order perturbation theory (CASPT2), are often employed to recover the missing electron correlation from multiconfigurational zeroth-order wave functions. Here, we introduce the data-driven CASPT2 (DDCASPT2) method to capture dynamic electron correlation using features generated from lower-level electronic structure methods, such as Hartree-Fock and complete active space self-consistent field (CASSCF) theory. We examine the effects of system size, basis set size, and the number of two-electron excitations using a small, but diverse, set of molecules. We also provide insights into our physics-based feature set using SHapley Additive exPlanation (SHAP) analysis, a feature analysis method based on cooperative game theory. In this paper, we utilize these insights to introduce a DDCASPT2 method, which provides a machine-learning-based alternative to traditional single- and multistate CASPT2 for capturing dynamical electron correlation with near-CASPT2 quality accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.002
Open science0.0030.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.294
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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