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Record W4415431826 · doi:10.1021/acs.jctc.5c01333

Capturing Electron Correlation with Machine Learning through a Data-Driven CASPT2 Framework

2025· article· en· W4415431826 on OpenAlex
Grier M. Jones, Konstantinos D. Vogiatzis

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Chemical Theory and Computation · 2025
Typearticle
Languageen
FieldMaterials Science
TopicMachine Learning in Materials Science
Canadian institutionsDairy Farmers of OntarioUniversity of Toronto
FundersDivision of Chemistry
KeywordsElectronic correlationCorrelationPerturbation (astronomy)Complete active spacePerturbation theory (quantum mechanics)Set (abstract data type)Space (punctuation)Parameter space

Abstract

fetched live from OpenAlex

Multireference perturbation theory methods, such as complete active space second-order perturbation theory (CASPT2), are often employed to recover the missing electron correlation from multiconfigurational zeroth-order wave functions. Here, we introduce the data-driven CASPT2 (DDCASPT2) method to capture dynamic electron correlation using features generated from lower-level electronic structure methods, such as Hartree-Fock and complete active space self-consistent field (CASSCF) theory. We examine the effects of system size, basis set size, and the number of two-electron excitations using a small, but diverse, set of molecules. We also provide insights into our physics-based feature set using SHapley Additive exPlanation (SHAP) analysis, a feature analysis method based on cooperative game theory. In this paper, we utilize these insights to introduce a DDCASPT2 method, which provides a machine-learning-based alternative to traditional single- and multistate CASPT2 for capturing dynamical electron correlation with near-CASPT2 quality accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.498
Threshold uncertainty score0.307

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.294
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it