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Record W4415438985 · doi:10.1302/1358-992x.2025.10.126

IMPACT OF SCHEDULED SPINE SURGERY FOR DEGENERATIVE SPINAL DISORDERS ON PATIENT HEALTH-RELATED QUALITY OF LIFE COMPARED TO THE GENERAL CANADIAN POPULATION

2025· article· en· W4415438985 on OpenAlexaffabout
Nisaharan Srikandarajah, John Murray, Christopher Nielsen, A.S. Cherry, Ragavan Manoharan, Aditya Raj, Meng Xu, Charles C. Bailey

Bibliographic record

VenueOrthopaedic Proceedings · 2025
Typearticle
Languageen
FieldMedicine
TopicSpine and Intervertebral Disc Pathology
Canadian institutionsToronto Western Hospital
Fundersnot available
KeywordsQuality of life (healthcare)CohortMyelopathyMedical diagnosisPopulationSpinal stenosisDegenerative DisorderCohort studyStenosis

Abstract

fetched live from OpenAlex

The national impact of spinal disorders and spine surgery on health related quality of life (HRQOL) has not been well characterized. Our objective was to compare baseline and 1-year HRQOL from the Canadian Spine Outcomes and Research Network (CSORN) registry to their age-sex matched estimations in the general population. Retrospective review of CSORN registry patients with degenerative cervical or thoracolumbar pathology was performed. The outcomes were baseline and 1-year, physical component (PCS) and mental component summary scores (MCS) from the Short Form Health Survey (SF-12). Age-sex specific means and standard deviation for PCS and MCS, baseline and 1-year post-operative, were calculated for the cohort and compared to their corresponding values from the Canadian general population (CGP). 5495 patients were analysed. Baseline mean PCS was 50.5 (SD 9) overall for the CGP, decreasing with each decade of age. Across all pathoanatomical diagnoses and chief clinical complaints, the mean PCS was 29.4 at baseline and 40.2 at 12 months postoperative in the CSORN group. PCS improvement was greatest for lumbar disc herniation/radiculopathy (13.3/12) and least for cervical stenosis / myelopathy (6.7/6.1). MCS for all diagnoses and chief complaints also substantially improved at 1-year, however both baseline and 1-year scores were within 1 SD of the CGP values. In a surgical cohort, compared to the CGP, degenerative spinal disorders are associated with a dramatic reduction of HRQOL across all age and sex groups regardless of diagnosis or clinical presentation. In a representative national surgical cohort, spine intervention was impactful in restoring HRQOL to within 1 standard deviation of the age-sex match CGP across all common degenerative diagnosis and symptom presentations. The relatively normative MCS scores of our entire surgical cohort reflects appropriate patient selection as it pertains to the negative surgical prognostic implication of poor mental health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.060
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.357
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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