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A Scoping Review of AI-Based Approaches for Detecting Autism Traits Using Voice and Behavioral Data

2025· review· en· W4415452041 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueBioengineering · 2025
Typereview
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsUniversité de Moncton
FundersUniversité de Moncton
KeywordsAutism spectrum disorderAutismStrengths and weaknessesKey (lock)Behavioural sciencesComputational model

Abstract

fetched live from OpenAlex

This scoping review systematically maps the rapidly evolving application of Artificial Intelligence (AI) in Autism Spectrum Disorder (ASD) diagnostics, specifically focusing on computational behavioral phenotyping. Recognizing that observable traits like speech and movement are critical for early, timely intervention, the study synthesizes AI's use across eight key behavioral modalities. These include voice biomarkers, conversational dynamics, linguistic analysis, movement analysis, activity recognition, facial gestures, visual attention, and multimodal approaches. The review analyzed 158 studies published between 2015 and 2025, revealing that modern Machine Learning and Deep Learning techniques demonstrate highly promising diagnostic performance in controlled environments, with reported accuracies of up to 99%. Despite this significant capability, the review identifies critical challenges that impede clinical implementation and generalizability. These persistent limitations include pervasive issues with dataset heterogeneity, gender bias in samples, and small overall sample sizes. By detailing the current landscape of observable data types, computational methodologies, and available datasets, this work establishes a comprehensive overview of AI's current strengths and fundamental weaknesses in ASD diagnosis. The article concludes by providing actionable recommendations aimed at guiding future research toward developing diagnostic solutions that are more inclusive, generalizable, and ultimately applicable in clinical settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.323
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.354
GPT teacher head0.445
Teacher spread0.091 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it