Transcatheter Tricuspid Valve Replacement in Torrential Tricuspid Regurgitation With Severe Right Ventricular Dysfunction
Bibliographic record
Abstract
BACKGROUND: Torrential tricuspid regurgitation (TR) with right heart failure poses management challenges, particularly in patients ineligible for surgery or transcatheter edge-to-edge repair. CASE SUMMARY: A 61-year-old man with torrential TR, severe right ventricular (RV) dilation (6.2 cm), and severe RV dysfunction presented with NYHA functional class IV symptoms. He was refractory to diuretics and inotropes and was declined for surgery, transcatheter edge-to-edge repair, and transplant. He underwent transcatheter tricuspid valve replacement with the LuX-Valve Plus. Postprocedure echocardiography showed improved RV end-diastolic area, RV fractional area change, and RV strain, with RV function improving to mild-moderate. He improved symptomatically but later died from unrelated complications. DISCUSSION: This case illustrates the feasibility of the LuX-Valve Plus in torrential TR with severe RV dysfunction and dilation. Procedural success and early signs of RV remodeling were achieved. TAKE-HOME MESSAGES: Transcatheter tricuspid valve replacement with the LuX-Valve Plus is viable in high-risk TR patients. Multiparametric RV assessment is essential for guiding intervention.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".