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Record W4415474521 · doi:10.1681/asn.2025xdedbvp8

Reasons for Home Hemodialysis Discontinuation in a Canadian Province

2025· article· en· W4415474521 on OpenAlexaffabout
Drew Hager, Reid Whitlock, Clara Bohm, Paul Komenda, Claire Harris, Jay P. Hingwala

Bibliographic record

VenueJournal of the American Society of Nephrology · 2025
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsUniversity of British ColumbiaOrthopaedic Innovation CentreUniversity of Manitoba
Fundersnot available
KeywordsDiscontinuationHemodialysisHome hemodialysisMEDLINE

Abstract

fetched live from OpenAlex

Background: Home hemodialysis (HHD) utilization is greater than 8% in Manitoba, Canada. Despite this, many patients stop HHD within the first several years. The present study aims to identify local rates of HHD discontinuation and the associated reasons, including potentially modifiable causes of technique failure. Methods: The target population includes adults in Manitoba, Canada with kidney failure who began HHD between January 1st, 2017 and December 31st, 2023. Data was collected retrospectively from an electronic health record and chart review. HHD discontinuation was defined as stopping for greater than sixty days. Results: During the study period, 266 patients completed HHD training. In total, 142 patients discontinued HHD with a mean time of 751 days (range 24 to 2225 days). The rates of discontinuation and technique failure at 12 and 36 months are reported in Table 1. A qualitative description of the psychosocial reasons for technique failure are outlined in Figure 1. Conclusion: Rates of HHD discontinuation in Manitoba, Canada are similar to previous published administrative database and program reviews. Our findings should encourage leaders in HHD to standardize technique failure as a key performance indicator, develop local initiatives to support patients with modifiable psychosocial reasons for technique failure, and encourage providers to discuss end of life goals of care when stopping HHD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.335

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.004
Science and technology studies0.0050.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.273
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueJournal of the American Society of Nephrology→Same topicDialysis and Renal Disease Management→French-language works237,207→