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Record W4415493823 · doi:10.1038/s43247-025-02809-w

Fragmented deoxyribonucleic acid could be extractable from Mars’s surface rocks

2025· article· en· W4415493823 on OpenAlexfundno aff
María‐Paz Zorzano, Jyothi Basapathi Raghavendra, Daniel Carrizo, Fuencisla Cañadas Blasco, Mariana Reyes‐Prieto, Giuseppe D’Auria, Javier Martín‐Torres

Bibliographic record

VenueCommunications Earth & Environment · 2025
Typearticle
Languageen
FieldPhysics and Astronomy
TopicPlanetary Science and Exploration
Canadian institutionsnot available
FundersEuropean Regional Development FundUK Research and InnovationHorizon 2020 Framework ProgrammeAgencia Estatal de InvestigaciónMinisterio de Ciencia, Innovación y UniversidadesLakehead UniversityNatural Environment Research CouncilOxford Nanopore Technologies
KeywordsMartian surfaceMartianSedimentary rockRadiolysisCarbon fibersEarth (classical element)Total organic carbonDNA

Abstract

fetched live from OpenAlex

Detecting biomolecules in rocks is vital for understanding life’s evolution on Earth and its possible existence on Mars. The Curiosity rover measured Total Organic Carbon (TOC) levels of 201–273 ppm in 3500 million years (Ma)-old Martian mudstones exposed to radiation for 78 ± 30 Ma. Here we investigate whether deoxyribonucleic acid (DNA), a unique biological polymer, can be recovered under comparable conditions. We extracted and sequenced DNA from terrestrial sedimentary rocks with TOC ranging from 182 to 63,000 ppm, yielding 184,000 to 3.8 million nucleobases from a 0.5 g rock sample. After exposure to 10.45 MGy of gamma radiation, equivalent to 136 Ma on the Martian surface, we measured a radiolytic constant of K = 0.17 MGy⁻¹ in microbialite (2800-year-old) and oxide iron formation (2930 Ma old) samples. Despite fragmentation, 1.48–8.45% of sequences remained taxonomically identifiable, demonstrating that DNA fragments can persist in rocks for over 100 Ma. Taxonomically identifiable DNA can be recovered from terrestrial rocks containing as little as 182 ppm of total organic carbon after exposure to radiation equivalent to 136 million years on Mars, suggesting that biosignatures could remain detectable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.851
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.237
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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