MétaCan
Menu
Back to cohort
Record W4415513550 · doi:10.5376/tgg.2025.16.0009

Functional Characterization of a Transgenic Barley Line Expressing Anti-Fungal Protein

2025· article· W4415513550 on OpenAlexvenueno aff
Miao Li

Bibliographic record

VenueTriticeae Genomics and Genetics · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicTransgenic Plants and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsTransgeneAntifungalGeneGenetically modified cropsImmune systemInnate immune systemHordeum vulgareGenetically modified mouseCrop

Abstract

fetched live from OpenAlex

Fungal diseases pose a serious threat to barley yield and quality, and it is difficult to breed highly resistant varieties quickly using traditional methods. Antifungal proteins, as crucial components of a plant’s innate immune system, have multiple defense functions (like breaking down cell walls, damaging membranes, and inhibiting pathogens), offering a new strategy for improving crop disease resistance. This study describes the sources and functions of antifungal genes, analyzes transgenic barley materials expressing antifungal proteins, and systematically characterizes their molecular, biochemical, and biological functions. Gene expression levels and protein accumulation in the transgenic plants were examined using qRT-PCR and Western blot, and tissue-specific expression was investigated via immunolocalization. The study also summarizes three case studies: a chitinase-producing barley from Japan’s NARO institute, an antimicrobial peptide-expressing line developed by ICRISAT, and a BDAI-overexpressing line from the University of Copenhagen. These cases further demonstrate the feasibility and promising prospects of using antifungal protein genes in transgenic strategies. The findings provide important evidence that genetic engineering can enhance barley’s disease resistance, and they offer theoretical and practical guidance for breeding disease-resistant crops.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.051
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.237
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueTriticeae Genomics and GeneticsSame topicTransgenic Plants and ApplicationsFrench-language works237,207