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Record W4415524932 · doi:10.2460/ajvr.25.05.0156

Ex vivo energy restriction in obese cats reveals more amino acid and vitamin intakes below recommendations with over-the-counter compared to veterinary weight-loss diets

2025· article· en· W4415524932 on OpenAlexaff
Caitlin Grant, Hannah Godfrey, Tonya M. Palermo, Anna K. Shoveller, Marica Bakovic, Shauna L. Blois, Adronie Verbrugghe

Bibliographic record

VenueAmerican Journal of Veterinary Research · 2025
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Medicine and Surgery
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsNutrientVitaminEx vivoCATSEnergy requirementObesityFood intakeAmino acidCaloric theory

Abstract

fetched live from OpenAlex

Objective: To determine whether cats meet National Research Council (NRC) recommendations for essential nutrient intake when energy restricted on various diets. Methods: 3 diets for each diet group-veterinary weight loss, over-the-counter low calorie (LOWCAL), and OTC adult maintenance (ADULT)-were analyzed for amino acids and vitamins. Theoretical nutrient intakes with each diet under energy restriction were calculated using body weight (BW) and body condition score data of 16 adult obese cats from a previous in vivo weight-loss study. Six energy calculations (R1-6) were used: R1, 70 kcal/current BW0.75; R2, 0.8 X 70 kcal/cBW0.75; R3, 70 kcal/ideal BW (iBW)0.75; R4, 0.6 X 130 kcal/cBW0.4; R5, 0.8 X 70 kcal/iBW0.75; and R6, 0.6 X 130 kcal/iBW0.4. Calculated intakes were compared to NRC recommended allowance (RA) and minimum requirements for adult cats. Results: Crude protein intake was below RA for LOWCAL at R4 and ADULT at R6 and below minimum requirements for ADULT at R6. Tryptophan and phenylalanine plus tyrosine intakes were below RA for ADULT at R4. Choline intake was below RA for veterinary weight loss at R2 and R4 through R6, for LOWCAL at R4 and R6, and for ADULT at R1 through R6. Conclusions: Theoretical energy restriction using purpose-formulated weight-loss food resulted in only choline being below NRC recommendations. Most nutrient intakes met NRC recommendations for LOWCAL and ADULT, except for crude protein, tryptophan, phenylalanine plus tyrosine, and choline intakes. Clinical Relevance: Veterinary professionals should exercise caution when restricting energy for weight loss, particularly with over-the-counter diets, as they may not meet essential nutrient requirements at lower caloric intakes. Veterinary weight-loss foods are recommended to reduce the risk of nutrient deficiencies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.545
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.412
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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