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A DISBIOSE DA MICROBIOTA SUBGENGIVAL E O PARTO PREMATURO: UMA REVISÃO SISTEMÁTICA

2025· article· W4415600773 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueRevista Interfaces Saúde Humanas e Tecnologia · 2025
Typearticle
Language
FieldHealth Professions
TopicHealthcare Regulation
Canadian institutionsnot available
Fundersnot available
KeywordsDysbiosisCohortPregnancyCohort studyPeriodontitisSystematic reviewPremature birth

Abstract

fetched live from OpenAlex

The mechanism of association between periodontitis and increased risk of adverse pregnancy outcomes is still a gap in scientific knowledge. The objective of this systematic review was to systematize knowledge about the association between the level of dysbiosis of the subgingival microbiota and prematurity. This is a cross-sectional, case-control or cohort study were eligible in this systematic review, searched in PubMed / MEDLINE, Web of Science, SCOPUS, Scielo, Lilacs, published until April 2020. This search was conducted using the descriptors: " Periodontitis", "Periodontal Disease", "Oral Dysbiosis", "Oral Microbiome", "Prematurity" and "Preterm". The outcomes were premature birth or premature rupture of membranes. The Newcastle - Ottawa scale was used by two independent reviewers to assess the quality of the studies. As a result, 266 studies were relevant in this systematic review. 59 articles were selected to read the full text. The inclusion criteria were met by seventeen studies: nine case-control studies, three cross-sectional studies and five cohort studies. The findings showed that the increased risk of premature birth may be associated with the degree of periodontal dysbiosis, with the main action being the green complex periodontopathogens, as long as they are grouped with the red and orange complexes. This systematic review indicates that there may be an association between dysbiosis in the subgingival microbiota and prematurity outcomes, highlighting the non-exclusive contribution of traditional key pathogens of periodontitis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.579
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.004
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0010.002
Science and technology studies0.0030.001
Scholarly communication0.0010.001
Open science0.0030.002
Research integrity0.0030.005
Insufficient payload (model declined to judge)0.0040.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.093
GPT teacher head0.419
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it