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Record W4415601601 · doi:10.12771/emj.2025.00934

Strengthening the reporting of observational studies in epidemiology using Mendelian randomization (STROBE-MR): a Korean translation of explanation and elaboration

2025· article· en· W4415601601 on OpenAlexafffund
Veronika Skrivankova, Rebecca C. Richmond, Benjamin Woolf, Neil M Davies, Sonja A. Swanson, Tyler J. VanderWeele, Nicholas J. Timpson, Julian P. T. Higgins, Niki Dimou, Claudia Langenberg, Elizabeth Loder, Robert M. Golub, Matthias Egger, George Davey Smith, J. Brent Richards

Bibliographic record

VenueThe Ewha Medical Journal · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Associations and Epidemiology
Canadian institutionsMcGill UniversityJewish General Hospital
FundersMedical Research CouncilZonMwNational Institutes of HealthSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungPublic Health AgencyUniversity of BristolEconomic and Social Research CouncilWorld Health OrganizationEuropean CommissionKing's College LondonPublic Health Agency of CanadaDepartment of Health and Social CareJewish General HospitalNational Institute for Health and Care ResearchNIHR Bristol Biomedical Research CentreCanadian Institutes of Health ResearchNational Science FoundationCompute CanadaNorges ForskningsrådCancer Research UKNederlandse Organisatie voor Wetenschappelijk OnderzoekWellcome Trust
KeywordsMendelian randomizationObservational studyElaborationEpidemiologyTranslation (biology)Randomization

Abstract

fetched live from OpenAlex

멘델 무작위화(Mendelian randomization, MR) 연구는 조절 가능한 노출(modifiable exposure)이 건강결과에 미치는 인과효과(causal effect)를 더 잘 이해하게 해 주지만, 그 근거는 종종 보고가 불충분함으로 인하여연구 결과의 해석과 적용에 한계가 있을 수 있다. 보고지침은 흔히 무슨 연구를 하고 무엇을 발견했는지 독자가 쉽게 이해하도록 돕는다. STROBE-MR(관찰연구의 멘델 무작위화를 활용한 보고지침)은 MR 연구를 명확하고 투명하게 보고하도록 돕는다. STROBE-MR을 논문 작성에 활용하면 독자, 심사자, 학술지 편집인이 MR 연구의 보고 품질과 완성도를 평가하는 데 도움이 될 것이다. 이 글은 STROBE-MR 체크리스트 20개 항목의 의미와 근거를 설명하고, 각 항목마다 사례를 제시해 독자가 잘 이해할 수 있는 논문 작성법을 설명하려고 하였다.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.493
metaresearch head score (Gemma)0.718
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.507
Threshold uncertainty score0.625

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.4930.718
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0050.007
Bibliometrics0.0100.010
Science and technology studies0.0020.009
Scholarly communication0.0060.005
Open science0.0040.010
Research integrity0.0100.016
Insufficient payload (model declined to judge)0.0070.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.157
GPT teacher head0.418
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainReporting
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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