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Record W4415604019 · doi:10.1111/acem.70167

GRADE‐Based Clinical Practice Guidelines for Emergency Department Delirium Risk Stratification, Screening, and Brain Imaging in Older Patients With Suspected Delirium

2025· article· en· W4415604019 on OpenAlexaff
Sangil Lee, Danya Khoujah, Debra Eagles, Maura Kennedy, Alexander X. Lo, Christian H. Nickel, Glenn Arendts, Luna Ragsdale, Justine Seidenfeld, Kerstin de Wit, Ines Luciani‐Mcgillivray, Christopher R. Carpenter, Shan W. Liu

Bibliographic record

VenueAcademic Emergency Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicIntensive Care Unit Cognitive Disorders
Canadian institutionsMcMaster UniversityOttawa Public HealthOttawa HospitalUniversity of Ottawa
FundersNational Institutes of Health
KeywordsDeliriumEmergency departmentClinical PracticeNeuroimagingMEDLINE

Abstract

fetched live from OpenAlex

OBJECTIVES: This portion of the Geriatric Emergency Department (GED) Guidelines 2.0 focuses on delirium in the emergency department (ED). METHODS: A multidisciplinary group applied the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and develop recommendations related to older ED patients with possible delirium. RESULTS: The GED Guidelines 2.0 Delirium Work Group derived six evidence-based recommendations for risk stratification, diagnosis, and brain imaging. To reduce universal screening, the Delirium Risk Score may be used to identify older adults at low risk for delirium, though the evidence certainty is very low. In adults over 65 admitted to ED observation units, Zucchelli's risk assessment tool (threshold ≥ 4) may stratify delirium risk, also with very low certainty. For adults over 75, the REDEEM Score may be used to identify low- or high-risk individuals, again with very low certainty. For diagnosis, 4AT, bCAM, CAM-ICU, mCAM, AMT-4, or RASS may be used to rule delirium in or out, based on very low certainty. The Delirium Triage Screen (DTS) may be used to rule out, but not to rule in, delirium, also with very low certainty. For diagnostic imaging, there is very low certainty of evidence to recommend for or against obtaining a head CT as part of the evaluation for older ED patients with delirium. All recommendations are conditional, reflecting very low certainty of evidence due to the lack of high-quality ED-based studies and comparative effectiveness research. CONCLUSION: Rigorous ED-based research is needed to strengthen evidence and guide delirium care for older adults in geriatric emergency medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.026
metaresearch head score (Gemma)0.141
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.037
Threshold uncertainty score0.140

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0260.141
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0060.013
Bibliometrics0.0150.008
Science and technology studies0.0030.001
Scholarly communication0.0050.003
Open science0.0080.005
Research integrity0.0070.009
Insufficient payload (model declined to judge)0.0140.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.434
Teacher spread0.377 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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