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Record W4415613396 · doi:10.1016/j.cjco.2025.10.010

Left Atrial Intracardiac Echocardiography to Assist Zero Fluoroscopy Pulse Field Atrial Fibrillation Ablation—A Beginner's Guide

2025· article· en· W4415613396 on OpenAlexaff
Intisar Ahmed, Carolina Guerrero-Pando, Nathan Denham, Mahbod Rahimi, Erica Muscat, Takahiro Hayashi, Carlo Duc-Malagisi, Vijay S. Chauhan, Andrew C.T. Ha, Abhishek Bhaskaran

Bibliographic record

VenueCJC Open · 2025
Typearticle
Languageen
FieldMedicine
TopicAtrial Fibrillation Management and Outcomes
Canadian institutionsAbbott (Canada)Toronto General HospitalMedtronic (Canada)University Health Network
Fundersnot available
KeywordsAtrial fibrillationCatheterFluoroscopyIntracardiac injectionPulse (music)Field (mathematics)Zero (linguistics)

Abstract

fetched live from OpenAlex

Background: Pulsed-field ablation (PFA) has emerged as a novel energy source for the management of atrial fibrillation (AF), offering improved tissue selectivity and a better safety profile. Although fluoroscopy has traditionally guided catheter positioning, the integration of intracardiac echocardiography (ICE), particularly from a left atrial (LA) vantage point, presents an opportunity for real-time visualization and enhanced procedural precision. In this paper, we describe a workflow for LA-ICE-guided PFA, without using fluoroscopy, and present preliminary data from our centre. Methods: All patients who underwent PFA for AF since December 2024 were screened, and those who underwent LA-ICE-guided ablation were included in the study. After patients provided informed consent, procedures were performed under general anesthesia with muscle relaxants to minimize stimulation of extracardiac muscles. Results: LA-ICE-guided PFA was performed in 100 consecutive patients with paroxysmal (73%) and persistent (27%) AF at a single centre. Zero-fluoroscopy (ZF) ablation was successfully performed in 28 patients, without any major complications. The challenges encountered during ZF ablation included enlarged atria, thick interatrial septum, venous tortuosity, aortic root aneurysm, and pacemaker leads. Visualizing the FlexCath sheath while crossing the interatrial septum and confirming its position in the left atrium immediately after crossing does require some effort, especially in a dilated left atrium. Conclusions: LA-ICE facilitates ZF-PFA for AF by offering superior visualization of the LA anatomy, continuous monitoring of catheter orientation, precise catheter positioning, and maintenance of catheter-tissue contact.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.685
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.358
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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