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Record W4415651695 · doi:10.30683/1927-7229.2025.14.12

Bladder Filling Variation in Cancer Cervix Patients Treated by Image Guided Radiation Therapy

2025· article· W4415651695 on OpenAlexvenueno aff
Anshuma Bansal, Neeru Bedi, Aditya Kumar Singla, Sunigdha Charry, Gurpreet Singh, Vinod Kumar Dangwal, Raja Paramjeet Singh

Bibliographic record

VenueJournal of Analytical Oncology · 2025
Typearticle
Language
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsnot available
Fundersnot available
KeywordsRadiation therapyStandard deviationCervixBladder cancerReproducibilityCarcinomaRadiation treatment planningCone beam computed tomography

Abstract

fetched live from OpenAlex

Variable bladder filling during radiotherapy for carcinoma cervix significantly affects the position of target volumes to be treated. This directly impacts the precision with which advanced radiotherapy plans are delivered using specific margins to target volumes. The aim is to study mean bladder volumes and mean range of bladder motion in all three dimensions in patients of carcinoma cervix treated with Image guided radiation therapy (IGRT), and compare them to the baseline planning Computed tomography (CT) scans. For this, a total number of 25 patients/ 150 CT scans, i.e. 25 planning scan and 125 CBCT (cone-beam CT) were analyzed. The bladder volumes and bladder wall dimension were analyzed using offline views of CBCT imaging, conducted weekly for cervix cancer patients, thus adding considerable understanding to the bladder wall motions. The mean bladder volume for all 25 patients was 263.41 cc with standard deviation of 110.174 cc. When mean CBCT bladder volumes of each patient were compared to their respective planning CT bladder volumes, P was found to be insignificant (p=0.25), showing consistent bladder filling or reproducibility during treatment. The mean ± standard deviation of bladder’s transverse, anteroposterior and supero-inferior dimension was 9.55 ± 0.923 cm; 6.92 ± 2.387 cm and 7.22 ± 0.967 cm. The mean supero-inferior bladder diameter had significant variation from that of the planning CT (7.84 ± 2.749 cm vs 6.92 ± 2.387) with p = 0.018. This study shows that more liberal margins should be considered in supero-inferior dimensions and considerable lesser margins could be given on the lateral sides, as there is less displacement in transverse diameter.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.534
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.358
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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