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Record W4415693064 · doi:10.1186/s12888-025-07511-x

Schizophrenia and sensory modulation problems: the relationship between severity, depression and sensory responsiveness

2025· article· en· W4415693064 on OpenAlexaboutno aff
Merve Şahin Can, Elif Gülşah Oğuz, Özge Demircan Tulacı

Bibliographic record

VenueBMC Psychiatry · 2025
Typearticle
Languageen
FieldMedicine
TopicSchizophrenia research and treatment
Canadian institutionsnot available
Fundersnot available
KeywordsPositive and Negative Syndrome ScalePsychopathologySensory systemSchizophrenia (object-oriented programming)Depression (economics)Major depressive disorderQuantitative sensory testingDepressive symptomsClinical significance

Abstract

fetched live from OpenAlex

BACKGROUND: Sensory modulation difficulties have been increasingly recognized in schizophrenia, with neurophysiological evidence indicating altered sensory processing. However, how these abnormalities relate to symptomatology and depressive features in daily life remains underexplored. This study aimed to investigate the associations between sensory responsiveness, symptom severity and depressive symptoms in individuals with schizophrenia. METHODS: A cross-sectional study was conducted with 74 outpatients diagnosed with schizophrenia. Participants completed the Sensory Responsiveness Questionnaire (SRQ), and clinicians rated symptom severity using the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia (CDSS). The relationship between schizophrenia symptoms, sensory integration and depressive symptoms was evaluated by correlation analysis. RESULTS: The mean age was 41.4 ± 12.5 years, with a mean duration of illness was 13.8 ± 11.1 years. The pleasure subscale of the SRQ was positively correlated with PANSS positive symptoms (r = 0.299, p < 0.001) and general psychopathology (r = 0.342, p < 0.001). Severity of depression was significantly associated with all PANSS subscales. CONCLUSION: These findings indicate altered sensory responses in individuals with schizophrenia, particularly in relation to positive symptoms and general psychopathology. This supports the clinical relevance of incorporating sensory profiling into assessment and therapeutic planning in schizophrenia care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.328
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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