Persistent Alterations of Brain and Behavior in Children With Low Prenatal Alcohol Exposure
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Background: Heavy prenatal alcohol exposure (PAE) is associated with alterations in behavior and cognitive and brain development. However, the effects of low levels of PAE on the brain and behavior remain unclear. In the current study, we aimed to investigate longitudinal changes in the brain and behavior in children with low levels of PAE compared with well-matched unexposed children. Methods: = 108, 9.52 [0.50] years at baseline) matched on socioeconomic status were selected from the ABCD (Adolescent Brain Cognitive Development) Study and were followed over 4 years with magnetic resonance imaging and Child Behavior Checklist (CBCL) scores. No children had adverse exposures to other substances. Results: Compared with unexposed children, children with low levels of PAE had persistently higher CBCL scores (worse behavior) and higher intracranial volumes over time. Conclusions: Our results provide further evidence of alterations in the brain and behavior associated with low levels of PAE across early adolescence, highlighting the importance of prevention and early intervention even with low levels of PAE.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it