Bilateral Granulomatous Keratic Precipitates Following Inadequate Antibiotic Coverage for Presumed Lyme Disease
Bibliographic record
Abstract
, is a multisystem infection with diverse ocular manifestations. Although ocular involvement is uncommon, it can include conjunctivitis, keratitis, uveitis, and optic neuropathy. We describe a 61-year-old man who developed bilateral mutton-fat keratic precipitates following a tick bite and incomplete systemic antibiotic coverage. His course was complicated by premature discontinuation of doxycycline and systemic corticosteroid exposure. Ophthalmic examination revealed bilateral granulomatous keratic precipitates without anterior chamber reaction. He was prescribed systemic azithromycin and referred to an infectious disease specialist for further evaluation. At the one-month follow-up, the patient demonstrated complete resolution of keratic precipitates and anterior chamber inflammation after completing azithromycin therapy, without the need for adjunctive corticosteroid use. This case underscores the importance of considering Lyme disease in the differential diagnosis of bilateral granulomatous keratic precipitates. Diagnostic challenges included an early false-negative serologic result, premature discontinuation of antibiotics, and corticosteroid exposure without adequate antimicrobial coverage. Bilateral granulomatous keratic precipitates may represent an early ophthalmic marker of systemic Lyme disease. Prompt recognition, initiation of systemic antibiotic therapy, and referral to an infectious disease specialist are essential to prevent long-term sequelae.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".