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Record W4415779866 · doi:10.1111/hdi.70031

Effect of Aerobic Combined Resistance Exercise in Dialysis on Restless Legs Syndrome: A Randomized Controlled Study

2025· article· en· W4415779866 on OpenAlexvenueno aff
Amin Li, Liqin Ye, Di Zhang, Wenwei Lu

Bibliographic record

VenueHemodialysis International · 2025
Typearticle
Languageen
FieldMedicine
TopicRestless Legs Syndrome Research
Canadian institutionsnot available
Fundersnot available
KeywordsRandomized controlled trialHemodialysisDialysisAerobic exerciseRestless legs syndromeAnxietySleep quality

Abstract

fetched live from OpenAlex

PURPOSE: To analyze the effects of aerobic combined resistance exercise in dialysis on restless legs syndrome (RLS), sleep quality, anxiety, depression, and quality of life of maintenance dialysis patients. METHODS: 59 patients who underwent maintenance hemodialysis combined with RLS in the blood purification center of Taihe County People's Hospital of Anhui Province from September to December 2024 were selected as the study subjects. The study subjects were divided into 30 cases of the control group and 29 cases of the intervention group using a randomized numerical table. The control group received routine dialysis and health education. In contrast, the intervention group received aerobic combined resistance exercise in dialysis, similar to the control group, with the time controlled at about 40 min, three times a week for 12 weeks. We observed the severity of RLS (IRLS), Pittsburgh Sleep Quality Index (PSQI), self-rating anxiety scale (SAS), self-rating depression scale (SDS), and quality of life (the Kidney Disease Questionnaire, KDQ) in the two groups before and after 12 weeks of intervention. RESULTS: There was no statistical difference in IRLS, PSQI, SAS, SDS, and KDQ scores between the two groups before the intervention (p > 0.05). After 12 weeks of intervention, IRLS, SAS, and SDS scores of the intervention group were lower than those of the control group (p < 0.05). Notably, the intervention group showed significantly improved PSQI scores (p < 0.05). The KDQ scores were higher than those of the control group, and the differences were all statistically significant (p < 0.05). CONCLUSION: Aerobic combined resistance exercise in dialysis can improve the symptoms of RLS in maintenance hemodialysis patients, enhance sleep quality, reduce negative emotions such as anxiety and depression, and improve quality of life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0040.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.327
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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