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Record W4415814970 · doi:10.1590/1678-4324-2025250518

Spectrophotometric Detection of Free Mercury(II) Ions in Thimerosal and Aqueous Media Using8-Hydroxyquinoline Functionalized Gold Nanoparticles

2025· article· en· W4415814970 on OpenAlexaff
Éder José dos Santos, Amanda Beatriz Herrmann, Jhulia Caroline Zanuto, Bruna Hilzendeger Marcon, Ana Julia Curioni Rodrigues, Ralph E. Sturgeon

Bibliographic record

VenueBrazilian Archives of Biology and Technology · 2025
Typearticle
Languageen
FieldChemistry
TopicMolecular Sensors and Ion Detection
Canadian institutionsNational Research Council CanadaMétis National Council
Fundersnot available
KeywordsDetection limitColloidal goldThimerosalAqueous mediumNaked eyeMetal ions in aqueous solutionPreservative

Abstract

fetched live from OpenAlex

Abstract A spectrophotometric method for determination of free Hg(II) ions in solutions of thimerosal and drinking water using AuNPs functionalized with 8-hydroxyquinoline (8HQ) is presented. The characterization of synthesized AuNPs was realized by UV/Vis spectra, SP-ICP-MS and TEM, with mean size of 21.2 ± 0.4 nm. The synthesized AuNPs were stable for about 65 days when protected from light and stored in polypropylene bottles under refrigeration at 4.0 ºC. Optimal conditions for colorimetric detection of Hg(II) were investigated, with the analytical wavelength being defined at 650 nm and ideal pH of the samples 7.0 ± 0.5. Over the concentration range 10 to 20 µmol L-1 detection of Hg(II) with the naked eye is possible due to the rapid color change of the medium from red to blue. However, for lower concentration ranges, between 0.5 to 5.0 µmol L-1, addition of 20 µL of 2.5 mol L-1 NaCl induces aggregation of nanoparticles, enhancing the detection limit to 0.1 µmol L-1. The selectivity of this approach was demonstrated in the presence of other metal ions. This fit-for-purpose sensor was successfully applied to the determination of free Hg(II) ions in thimerosal, a common preservative for vaccines, and has been adopted for use by Tecpar`s laboratory of the Parana Institute of Technology (Curitiba, Brazil).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.118
Threshold uncertainty score0.501

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.225
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueBrazilian Archives of Biology and TechnologySame topicMolecular Sensors and Ion DetectionFrench-language works237,207