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Record W4415815935 · doi:10.2196/78023

Dental Caries Detection in Children Using Intraoral Scanners Featuring Fluorescence: Diagnostic Agreement Study

2025· article· en· W4415815935 on OpenAlexvenueno aff
Bree Jones, Tong Chen, Stavroula Michou, Nicky Kilpatrick, Nigel Curtis, David Burgner, Christoph Vannahme, Mihiri Silva

Bibliographic record

VenueJMIR Public Health and Surveillance · 2025
Typearticle
Languageen
FieldDentistry
TopicDental Health and Care Utilization
Canadian institutionsnot available
FundersNational Health and Medical Research CouncilMedical Research CouncilState Government of VictoriaMurdoch Children's Research InstituteChildren’s Hospital of Wisconsin Research Institute
KeywordsLimits of agreementPopulationDiagnostic testDiagnostic accuracyRoot caries

Abstract

fetched live from OpenAlex

Background: Dental caries is a common chronic disease in children. Digital tools such as intraoral scanners (IOSs) may offer an efficient, scalable alternative to conventional visual examination for dental caries detection. IOSs are handheld devices that generate 3-dimensional (3D) models of the teeth and surrounding structures. Recent advances incorporating fluorescence technology into scanner hardware offer the potential for supporting dental caries detection. However, the performance of digital caries detection methods using 3D models that include both color and fluorescence in children's teeth remains unknown. Objective: This study aimed to assess the diagnostic agreement between visual examination and on-screen assessment of 3D models generated by an IOS in color and supplemented with fluorescence for caries detection in primary teeth. Methods: Children participating in a clinical trial (n=216, mean age 5.6, SD 0.4 y) underwent visual examination using the International Caries Detection and Assessment System (ICDAS) and intraoral scanning using the TRIOS 4 IOS. Four trained registered dental practitioners independently assessed each participant's 3D models in color and then supplemented with fluorescence, using a previously validated ICDAS index modified for on-screen assessments of 3D models. All 3D models were assessed again after 4 weeks. The time taken for intraoral scanning and on-screen assessment was recorded. Multilevel logistic regression was used to estimate and compare the likelihood of detecting caries between methods, and Bland-Altman plots were used to visualize agreement. Analyses were performed at the initial (ICDAS ≥01), moderate (ICDAS ≥03), and extensive (ICDAS ≥05) dental caries thresholds. Intraclass correlation coefficient (ICC) estimated method agreement and examiner reliability. Results: Of 219 children enrolled, 216 completed dental assessments. A total of 9470 visible primary tooth surfaces were included in the analysis. The average time taken for on-screen assessment of each 3D model (color with fluorescence) was 3.5 (SD 2.3) minutes. The likelihood of detecting caries using color assessment of 3D models was similar to visual examination at all disease thresholds: initial (odds ratio [OR] 1.1, 95% CI 1.0-1.3), moderate (OR 0.9, 95% CI 0.7-1.1), and extensive (OR 1.0, 95% CI 0.7-1.3). When color assessments were supplemented with fluorescence, the likelihood of detecting caries was 30% higher at the initial threshold relative to visual examination (OR 1.3, 95% CI 1.1-1.5) and similar at the moderate (OR 0.9, 95% CI 0.7-1.1) and extensive thresholds (OR 0.9, 95% CI 0.7-1.3). Bland-Altman plots showed a high level of agreement at both moderate and extensive thresholds. Agreement between methods was high (ICC 0.9, 95% CI 0.9-1.0). Intra- and inter-examiner reliability using intraoral scans ranged from good to excellent (ICC 0.8-1.0). Conclusions: On-screen assessment of 3D models in color demonstrated the highest agreement with visual examination for caries detection across all disease thresholds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.062

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.023
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.319
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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