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Record W4415831506 · doi:10.1016/j.identj.2025.105835

Perioperative Management Of Anticaogulated Patients In Oral Surgery: Tranexamic Acid

2025· article· en· W4415831506 on OpenAlexaff
Mark E Perry, Sandra Ammonn

Bibliographic record

VenueInternational Dental Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicBlood transfusion and management
Canadian institutionsHuntington Society of CanadaEmmanuel Bible College
Fundersnot available
KeywordsTranexamic acidHemostasisPerioperativeAnticoagulantDental extractionAntifibrinolyticOral surgeryCoagulation

Abstract

fetched live from OpenAlex

Introduction Managing anticoagulated patients in oral surgery requires balancing bleeding risk with thromboembolic prevention. Discontinuing anticoagulants increases thrombotic risk, while maintaining them may lead to excessive bleeding. Topical 4.8% tranexamic acid (TXA), an antifibrinolytic agent, stabilizes clot formation without affecting systemic coagulation. This case highlights the use of TXA as a local hemostatic measure in an anticoagulated patient undergoing tooth extraction for implant placement. Case description A male patient on anticoagulants required extraction before dental implant placement. • Preoperative: No anticoagulation adjustment; TXA rinse (4.8%, 2 min). • Intraoperative: Atraumatic extraction, Gentle irrigation with TXA, TXA-soaked gauze applied. • Postoperative: TXA mouth rinses (10 mL, 2 min, 4×/day for 2 days). Follow-ups at 24 hours, 1 week, and 2 weeks. Discussion Hemostasis was achieved without excessive bleeding or complications. Topical TXA effectively controlled bleeding while allowing continuous anticoagulation, aligning with current evidence-based guidelines. Studies support TXA’s role in reducing oral surgery bleeding without systemic risks. Conclusion/clinical significance 4.8% TXA is a safe, effective hemostatic adjunct for anticoagulated patients undergoing oral surgery. Its use eliminates the need for anticoagulant discontinuation, minimizing both thrombotic and bleeding risks. This case supports TXA as a standard hemostatic strategy in oral surgery, warranting further study.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.074
Threshold uncertainty score0.394

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.285
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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