MétaCan
Menu
Back to cohort
Record W4415848646 · doi:10.1002/gin2.70047

Understanding the Determinants That Influence the Development and Implementation of Evidence‐Based Practice Guidelines During Health Emergencies: An Exploratory Sequential Mixed‐Methods Study Protocol

2025· article· en· W4415848646 on OpenAlexafffund
Gonzalo Bravo‐Soto, Shelly‐Anne Li, Gordon Guyatt, Nancy Santesso, Susan M. Jack, Thomas Agoritsas, François Lamontagne, John N. Lavis, Reem A. Mustafa, Bram Rochwerg, Wojtek Wiercioch, Linan Zeng, Ludovic Revéiz, Romina Brignardello‐Petersen

Bibliographic record

VenueClinical and Public Health Guidelines · 2025
Typearticle
Languageen
FieldHealth Professions
TopicHealth Policy Implementation Science
Canadian institutionsUniversité de SherbrookeMcMaster UniversityMcMaster University Medical CentreUniversity Health NetworkImpact
FundersCanadian Institutes of Health Research
KeywordsGuidelineProtocol (science)Health careExploratory researchData collectionSample (material)Process (computing)Qualitative research

Abstract

fetched live from OpenAlex

ABSTRACT Introduction The COVID‐19 pandemic highlighted the crucial role of evidence‐based practice guidelines (EBPGs) in healthcare systems. Reliable and timely guidelines are essential in health emergencies. This study aims to identify and comprehensively understand the determinants that influence the development and implementation of EBPGs during health emergencies from the perspective of guideline developers and implementers. In this article, we describe the study protocol. Methodology We will conduct an exploratory sequential mixed‐methods study composed of four phases: (I) a qualitative descriptive study to document the experiences of guideline developers and implementers and use this data to generate a list of determinants that influence the development and implementation of EBPG; (II) exploratory integration for survey development and validation using the data of phase I; (III) cross‐sectional study to administer the survey to a large sample and estimate the frequency and perceived impact of those determinants; (IV) interpretation of the results: a combination of qualitative and quantitative findings through the narrative description and joint displays to generate a comprehensive understanding of those determinants. We will explore if results vary across subgroups of interest (participants' roles, gender, and type of organization). We will include people worldwide from five groups participating in an EBPG development and implementation process during the pandemic. Discussion This study will provide insights into the determinants that influence the development and implementation of EBPGs during health emergencies. Its potential impact includes improving future health emergency preparedness, addressing equity gaps, and enhancing guideline development and implementation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.106
metaresearch head score (Gemma)0.103
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.106
Threshold uncertainty score0.562

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1060.103
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0040.004
Science and technology studies0.0040.002
Scholarly communication0.0040.004
Open science0.0030.004
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0220.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.951
GPT teacher head0.796
Teacher spread0.155 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueClinical and Public Health GuidelinesSame topicHealth Policy Implementation ScienceFrench-language works237,207