The role of insulin and octopamine in regulating energy homeostasis and locomotion in insects
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Maintaining energy homeostasis is a fundamental requirement for survival. At the core, animals must balance periods of food-searching and feeding with other essential, energy-consuming behaviors. This also applies to insects, which spend a considerable fraction of their lifetime foraging - sometimes under extreme conditions. The motivation to search for food is increased by a lack of energy stores, which drives a hunger signal generated by the interplay between the depletion of energy stores, enteroceptors, and neuroendocrine signaling pathways. These changes alter the internal state of the animal, which modulates the activity of sensorimotor circuits to drive behavioral changes. Here, we review recent insights into the modulation of locomotor activity and foraging by two systems that play critical and antagonistic roles in linking energy homeostasis to behavioral changes in insects and other animals: the insulin and the octopamine system.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.004 |
| Science and technology studies | 0.000 | 0.002 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it