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Record W4415927164 · doi:10.12659/ajcr.949363

Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report

2025· article· en· W4415927164 on OpenAlex
Gabrielle Denault, Anne-Sophie Lê, Stéphane Perron

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAmerican Journal of Case Reports · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeme Oxygenase-1 and Carbon Monoxide
Canadian institutionsCentre Hospitalier de l’Université de MontréalMcGill UniversityUniversité de Montréal
Fundersnot available
KeywordsAnginaProvocation testChest painVasospastic anginaCoronary vasospasmTobacco smoke

Abstract

fetched live from OpenAlex

BACKGROUND Vasospastic angina (Prinzmetal angina) has been linked to many risk factors, including tobacco smoking. Although numerous studies have reported associations between air pollutants and cardiovascular outcomes, the relationship with vasospastic angina remains poorly documented. We report the case of a 45-year-old man with normal coronary arteries who developed episodes of chest pain due to vasospastic angina following inhalation of campfire smoke. CASE REPORT A 45-year-old man with a history of eczema, dyslipidemia, Gramineae allergy, and past tobacco use participated in a 3-day camping trip during which he was regularly exposed to campfire smoke. Two days later, and with an otherwise negative environmental history, he began experiencing episodes of chest pain at rest. Exercise-stress electrocardiography was clinically negative. Coronography showed no significant stenosis. Cardiac magnetic resonance imaging (MRI) showed no myocardial fibrosis. Positron emission tomography (PET) showed no myocardial ischemia or necrotic sequelae. The diagnosis of vasospastic angina was eventually confirmed by an acetylcholine provocation test. While exposure to campfire smoke may have acted as a trigger, other contributing factors, including prior tobacco use, allergy history, and potential genetic susceptibility, could also have contributed to the development of vasospastic angina in this patient. CONCLUSIONS This case report suggests that air pollution exposure, such as campfire smoke, can act as a trigger for vasospastic angina and highlights the need for further studies to assess this relationship. From a public health perspective, identifying and avoiding potential triggers remains an important measure that can complement existing preventive strategies for cardiovascular diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.790

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.273
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it