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Record W4415973460 · doi:10.1016/j.epsc.2025.103145

Large aneurysmal dermatofibroma mimicking melanoma in an adolescent: A case report

2025· article· en· W4415973460 on OpenAlexaff
E. C. H. Lim, Andreana Bütter

Bibliographic record

VenueJournal of Pediatric Surgery Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicSarcoma Diagnosis and Treatment
Canadian institutionsWestern UniversityLondon Health Sciences CentreChildren's Hospital of Western OntarioHamilton Health Sciences
Fundersnot available
KeywordsHemosiderinDermatofibromaHistopathologyGiant cellMelanomaHistopathological examinationPathologicalFibromaLesion

Abstract

fetched live from OpenAlex

Hemosiderotic dermatofibroma (HDF) is an infrequent variant of dermatofibroma, made up of small blood vessels, hemosiderin deposits, and extravasated erythrocytes. HDF closely resembles melanoma, with irregular borders and colour changes on clinical examination and atypical cell organization on dermoscopy and can pose a diagnostic dilemma. We report the case of a large (5cm) subcutaneous hemosiderotic/aneurysmal DF (H/ADF) that appeared on the flank of 17-year-old, otherwise healthy, male patient. The mass evolved over two years, with purple discoloration noticed three months prior. Clinical examination revealed a palpable moveable mass overlying the left hip in the subcutaneous tissues measuring approximately 4 x 4 cm. Because of both the substantial size of the mass and diagnostic uncertainty, the decision was made to proceed with surgical resection. The lesion was resected without complication, although there was copious bleeding initially. Pathological findings showed a dermatofibroma, cellular subtype, with aneurysmal change. Sections showed a solid, cellular proliferation composed of plump ovoid to spindle cells arranged in a storiform pattern and short fascicles punctuated by areas of hemorrhage and associated hemosiderin pigment deposition. Occasional multinucleated giant cells were seen. At 1 month follow-up, the patient was in good condition, and completely asymptomatic. There was no recurrence. Pediatric surgeons should be aware that rare dermatofibroma variants, such as aneurysmal dermatofibroma, can clinically resemble melanoma and should be treated with excisional biopsy. Diagnosis should always be confirmed with histopathology and immunohistochemistry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.301
Threshold uncertainty score0.925

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.300
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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