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Record W4416024624 · doi:10.1007/s40471-025-00373-7

Severe Maternal Morbidity: Fundamental Concepts

2025· article· en· W4416024624 on OpenAlex
K.S. Joseph, Sarka Lisonkova, Giulia M. Muraca, Ian Henderson, Tamar Wainstock, Neda Razaz, Suzan L. Carmichael, Marian Knight, Israel Yoles

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCurrent Epidemiology Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicMaternal and fetal healthcare
Canadian institutionsHamilton Health SciencesMcMaster UniversityBC Children's HospitalChildren's & Women's Health Centre of British ColumbiaUniversity of British Columbia
Fundersnot available
KeywordsPerspective (graphical)PopulationIntervention (counseling)Component (thermodynamics)EpidemiologyMEDLINEOutcome (game theory)

Abstract

fetched live from OpenAlex

Despite the importance of severe maternal morbidity (SMM) as a medical concern, there is a lack of consensus on several issues related to this topic. This article reviews fundamental concepts associated with SMM, and provides a historical and scientific perspective on these critical issues. SMM is defined as the population rate of serious illnesses in pregnancy, childbirth, or the puerperium. The SMM rate depends on the component severe maternal illnesses included in composite SMM, the rigor with which these components are defined, and the data sources used for surveillance (among others). These issues pose a serious challenge for spatiotemporal comparisons of SMM, especially for between-country comparisons of composite SMM rates. The different severe maternal illnesses included within composite SMM display substantial heterogeneity in terms of frequency, clinical burden of illness, and population impact. Other concerns include the need to address SMM in early pregnancy hospitalizations and postpartum readmissions; the need for nuanced interpretation of adjusted rates; and whether assigning a singular underlying severe illness is preferable to assigning one or more severe illnesses for each woman. Finally, the heterogeneity of the composite measure warrants careful consideration of the need for an all-inclusive composite outcome versus a more restricted/specific outcome depending on the study question or surveillance priority. Prevention programs addressing SMM need to focus on component illnesses and identify opportunities for intervention based on case reviews or epidemiologic analyses of risk factors for the specific illness. There is a lack of consensus on several concepts related to SMM, and this calls for a careful consideration of the clinical and epidemiologic issues related to quantifying and interpreting SMM rates.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.127
Threshold uncertainty score0.609

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.094
GPT teacher head0.451
Teacher spread0.357 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it