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Record W4416094175 · doi:10.1007/s00406-025-02143-4

Elevated defeatist performance beliefs predict state increases in negative symptoms in daily life in clinical high-risk for psychosis youth: implications for mobile health treatments

2025· article· en· W4416094175 on OpenAlexaff
Lauren Luther, Ian M. Raugh, Paul M. Grant, Aaron T. Beck, Vijay A. Mittal, Elaine F. Walker, Gregory P. Strauss

Bibliographic record

VenueEuropean Archives of Psychiatry and Clinical Neuroscience · 2025
Typearticle
Languageen
FieldPsychology
TopicDigital Mental Health Interventions
Canadian institutionsDouglas Mental Health University Institute
FundersNational Institute of Mental Health
KeywordsPsychosisMoodEveryday lifeMechanism (biology)Schizophrenia (object-oriented programming)Mood disordersYoung adult

Abstract

fetched live from OpenAlex

BACKGROUND: Negative symptoms are a strong predictor of conversion to a formal psychotic disorder in youth at clinical high-risk for developing psychosis (CHR). Identification of temporally precise mechanisms underlying increases in negative symptoms could enhance early intervention and specifically support the utility of mobile health treatments. Guided by Cognitive Behavioral models of psychopathology, we examine whether a core type of biased thinking-defeatist performance beliefs (DPB)-is a real-world mechanism of negative symptoms as well as a secondary symptom that is common in CHR youth: depressed mood. METHODS: CHR youth (n = 119) and healthy control (CN; 59) subjects completed ecological momentary assessment surveys assessing DPB, negative symptoms, and depressed mood for six days. RESULTS: CHR youth reported elevated DPB in daily life compared to CN. Greater DPB were associated with greater concurrent negative symptoms and depressed mood in daily life. Time-lagged analyses demonstrated that increased DPB at time t led to elevations in negative symptoms and depressed mood at t + 1 above and beyond the effects of the respective symptom at time t; DPB also varied across time of day, study day, day of the week, activity context, and social partners. CONCLUSIONS: DPB may be a promising shared mechanism contributing to negative symptoms and depressed mood in CHR youth in their daily life. Findings also provide proof-of-concept support for the utility of mobile health treatments targeting DPB by identifying key moments where DPB fluctuate in CHR youths' everyday environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.413
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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