Physical exercise training improves muscle strength and self‐esteem in children with intestinal failure
Bibliographic record
Abstract
Abstract Objectives Pediatric intestinal failure (IF) patients are less physically active compared to healthy peers, exhibit an altered body composition and low bone mineral density, which can be improved through physical activity. We assessed the effects of a tailored exercise intervention on physical fitness, nutritional status, and psychological functioning in children with IF. Methods Pediatric IF patients, still on and weaned off parenteral nutrition aged 6–18 years were eligible. Physical fitness ([sub]maximal exercise capacity, amount of physical activity, motor performance, strength, and core stability), nutritional status (body composition, energy expenditure, and laboratory parameters) and psychological functioning (fear, quality of life, fatigue, gastrointestinal symptoms, and self‐esteem) were assessed before and after an initial control period and after a 12‐week tailored exercise intervention. Results Sixteen participants (median age 12.2 years [10.5–14.6]) underwent baseline assessments, and eight were weaned off parenteral nutrition. Exercise capacity was normal, but the majority (63%) did not meet physical activity guidelines. Motor skills and muscle strength were impaired. Postintervention, exercise capacity in VO 2peak did not improve significantly, but workload in watt ( p < 0.01), muscle strength in various muscle groups ( p < 0.05), core stability ( p < 0.05), and self‐esteem ( p < 0.05) improved. Nutritional status remained unchanged. Baseline motor skills and change in VO 2peak were positively correlated ( R = 0.66, p < 0.05). Conclusions Our tailored exercise intervention improved muscle strength, core stability, and self‐esteem. Most participants do not meet physical activity recommendations and exhibit impaired muscle strength and motor skills, while exercise capacity is normal. Notably, participants with better baseline motor skills showed greater improvements in exercise capacity. Clinical Trial Registration Registration ID: NL8181, https://onderzoekmetmensen.nl/nl/trial/27466 .
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".