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Record W4416160968 · doi:10.17816/mser688243

Cognitive reserve among elderly patients with traumatic brain injury

2025· article· W4416160968 on OpenAlexaboutno aff
A. V. Lysenko, Н. М. Агарков

Bibliographic record

VenueMedical and Social Expert Evaluation and Rehabilitation · 2025
Typearticle
Language
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsnot available
Fundersnot available
KeywordsCognitive reserveTraumatic brain injuryCognitionEffects of sleep deprivation on cognitive performanceCognitive impairmentCognitive declineExecutive functionsMontreal Cognitive Assessment

Abstract

fetched live from OpenAlex

BACKGROUND: Traumatic brain injury (TBI) is damage to the brain caused by an external mechanical force, leading to temporary or permanent impairment of brain function and associated with deficits in information processing speed, attention, memory, speech, visuospatial perception, and executive functions. Cognitive reserve is defined as inherited or acquired mental skills that provide higher cognitive adaptability and protect against the effects of brain aging, diseases, or injuries; however, it remains insufficiently studied in patients with TBI. AIM: The work aimed to examine the characteristics of cognitive reserve in elderly patients with traumatic brain injury. METHODS: Fifty-seven individuals aged 60–74 years with TBI and 60 patients of the same age without brain injury were examined. Cognitive reserve was assessed using the Cognitive Reserve Index questionnaire, which includes questions on education, occupational activity, and leisure time. Mental status was evaluated using the MoCA and MMSE scales. RESULTS: Comparison between elderly TBI patients and age-matched controls showed that the overall cognitive reserve index was higher in the control group. Among 60–74-year-old TBI patients, the cognitive reserve index was significantly higher in those with mild TBI and lowest in those with severe TBI (p 0.001). Positive correlations were found between “driving a car” (r = 0.315, p 0.05) and “use of modern technologies” (r = 0.300, p 0.05) in elderly patients without trauma. At the same time, these characteristics were negatively correlated with moderate TBI (r = −0.273, p 0.05 and r = −0.404, p 0.05, respectively). CONCLUSION: Cognitive reserve makes a substantial contribution to the clinical profile of TBI in older age. The results demonstrated that cognitive reserve is associated with TBI severity, with more severe injuries corresponding to a lower cognitive reserve index.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.833
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.003
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.413
Teacher spread0.368 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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