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Record W4416167091 · doi:10.1111/bioe.70051

Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People

2025· article· en· W4416167091 on OpenAlexafffund
Derek So, Yann Joly, Robert Sladek

Bibliographic record

VenueBioethics · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsMcGill Genome Centre
FundersCanadian Institutes of Health Research
KeywordsNarrativeIdentity (music)Narrative identityBioethicsSocial identity theoryAffect (linguistics)Genome editingSocial identity approach

Abstract

fetched live from OpenAlex

Genome editing in human embryos could raise new ethical issues by changing future people's narrative and numerical identity. Most philosophers agree that some genetic modifications would have larger effects on identity than others, but they disagree on what criteria might explain these differences and have not supported their claims experimentally. We recruited 416 Americans through the crowdsourcing website Mechanical Turk. Participants were presented with 30 genetic modifications commonly discussed in bioethics and completed a questionnaire about how each modification might affect future people's narrative identity and social treatment. Perceived effects of genome editing on narrative identity correlate moderately with effects on social treatment, suggesting a large role for social construction. The largest changes to identity were associated with changing biological sex, enhancing intelligence, adding abilities from other species and introducing or preventing deafness. The smallest changes to identity were from making people right-handed, lowering the need for sleep, preventing dementia and changing eye or hair colour. Modifications of the same characteristic in opposite directions, such as making someone more or less aggressive, generally had significantly different effects on societal treatment but not on narrative identity. Specifying gender by describing the genetically modified person as a 'son' or 'daughter' did not have significant effects. These findings offer a new direction for research on genome editing and the identity of genetically modified people.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.017
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0040.007
Scholarly communication0.0040.002
Open science0.0000.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.390
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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