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Record W4416192970 · doi:10.1093/ejcts/ezaf329

European Respiratory Society and European Society of Thoracic Surgeons clinical practice guideline on fitness for curative intent treatment of lung cancer

2025· article· en· W4416192970 on OpenAlexfundno aff
Alessandro Brunelli, Georgia Hardavella, Rudolf M. Huber, Thierry Berghmans, Armin Frille, Maria Rodriguez, Ilona Tietzova, Lieven Depypere, Riccardo Asteggiano, Tim Batchelor, Adrien Costantini, Dirk De Ruysscher, Valérie Durieux, Corinne Faivre‐Finn, Mark K. Ferguson, Daniël Langer, Nándor Marczin, Blin Nagavci, Nuria Novoa, Cecilia Pompili, Janette Rawlinson, Annemiek Snoeckx, Thomy Tonia, Wouter H. van Geffen, Clare Williams, Edward Caruana, Pınar Akın Kabalak, Ulrich Mansmann, Vincent Fallet, Diego Kauffmann‐Guerrero, Marianne Paesmans, Amani Al Tawil, Nora Alhannoush, Andrew Creamer, Ismini Kourouni, Torsten Blum

Bibliographic record

VenueEuropean Journal of Cardio-Thoracic Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicLung Cancer Diagnosis and Treatment
Canadian institutionsnot available
FundersMedelaEuropean Society for Medical OncologyUniversity of TorontoDaiichi-SankyoBundesministerium für Bildung und ForschungUniversity of NottinghamEuropean Association for Cardio-Thoracic SurgeryUniversity of OxfordNovocureRegeneron PharmaceuticalsBeiGeneNovartis FoundationEli Lilly and CompanyAstraZenecaAtriCureInternational Association for the Study of Lung CancerSanofiEuropean Respiratory SocietySociety of Thoracic SurgeonsAmgenPfizerQueen Mary University of London
KeywordsGuidelineMultidisciplinary approachLung cancerInclusion (mineral)Clinical PracticeLung functionHealth careMEDLINENarrative review

Abstract

fetched live from OpenAlex

A multidisciplinary panel of lung cancer experts with a special interest in functional evaluation of lung cancer patients, and lung cancer patient representatives, has been facilitated by the European Society of Thoracic Surgeons and the European Respiratory Society to provide healthcare professionals with practical and up-to-date recommendations for the assessment of patients' fitness for curative intent treatments for lung cancer. The panel formulated four PICO (population, intervention, comparison and outcomes) questions and seven complementary narrative questions. Both types of questions were assigned to groups of at least two experts. A medical librarian conducted the literature searches, and the authors selected relevant studies based on predefined inclusion criteria. Risk of bias was assessed using the QUIPS (Quality in Prognosis Studies) tool. Data were summarised and the certainty of evidence was assessed with GRADE (Grading of Recommendations, Assessment, Development and Evaluations) and the Evidence to Decisions framework was used to formulate recommendations. A series of multidisciplinary recommendations was formulated about the utilisation of pulmonary function tests, split lung function values, exercise tests, cardiologic testing, and the role of prehabilitation, sublobar resections, risk scores and comorbidities in selecting patients for curative intent treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.020
Threshold uncertainty score0.076

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0140.025
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0050.004
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0040.003
Research integrity0.0060.007
Insufficient payload (model declined to judge)0.0060.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.439
Teacher spread0.361 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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