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Record W4416194069 · doi:10.3389/fnins.2025.1627888

Cross-modal neuroplasticity in partial hearing loss: a mini-review

2025· article· en· W4416194069 on OpenAlexafffund
Patricia V. Aguiar, Jennifer Preman, Brandon T. Paul

Bibliographic record

VenueFrontiers in Neuroscience · 2025
Typearticle
Languageen
FieldPsychology
TopicMultisensory perception and integration
Canadian institutionsToronto Metropolitan University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsNeuroplasticityPlasticityHearing lossSensory systemNeuroimagingHomeostatic plasticityPerceptionStructural plasticity

Abstract

fetched live from OpenAlex

Sensory loss induces adaptive neural changes in the remaining non-deprived senses, known as cross-modal plasticity. Recent proposals of cross-modal plasticity suggest that it is a top-down, dynamic phenomenon that can occur through the lifespan and is initiated whether sensory loss is total (as in blindness or deafness) or more subtle (mild-to-moderate partial sensory loss). However, it is unclear whether adaptive plasticity differs between total and partial loss, because there is less research on the latter condition. Here we reviewed neuroimaging research on cross-modal plasticity in adult humans with mild-to-moderate hearing loss and compared it to three claims derived from deafness research. First, cross-modal plasticity is thought to involve both intra-modal strengthening of remaining senses and cross-modal recruitment of deprived cortical areas, but we were unable to identify strong evidence of cross-modal recruitment in adults with partial hearing loss. Second, cross-modal plasticity is believed to arise through top-down connections and implicates cognitive function, which agreed with our findings. Third, cross-modal plasticity is believed to enhance perception in the non-deprived senses. No study in our review supported this claim, but it is possible that cross-modal plasticity in partial hearing loss results in stronger modulation of auditory function by intact senses. In addition, many study outcomes in humans with partial loss were inconsistent. Overall, it may be premature to conclude that cross-modal plasticity operates the same for partial and total forms of sensory loss in humans, and we provide several recommendations for testing these claims in future research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.036
Threshold uncertainty score0.511

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.389
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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