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Record W4416203199 · doi:10.32799/ijih.v21i1.45661

Implementation Barriers and Outcomes of a Provincial Prescribed Safer Supply Initiative among Indigenous People who use Substances amid COVID-19 and a Toxic Drug Crisis in British Columbia, Canada

2025· article· W4416203199 on OpenAlexfundvenueaboutno aff
Alexa Norton, Shawn Wood, Heather J. Spence, Omid Gheysar Gharamaleki, Katherine Hogan, Amanda Slaunwhite, Karen Urbanoski, Bernie Pauly, R David, Brittany Barker

Bibliographic record

VenueInternational Journal of Indigenous Health · 2025
Typearticle
Language
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsnot available
FundersCanadian Institutes of Health ResearchMinistry of Health, British ColumbiaMichael Smith Health Research BCVictoria General Hospital FoundationGovernment of Canada
KeywordsSAFERIndigenousReceiptMedical prescriptionPsychosocialLongitudinal studyWork (physics)Health careCohort

Abstract

fetched live from OpenAlex

Background: In 2020, British Columbia (BC) introduced Risk Mitigation Guidance to support the provision of prescribed safer supply (PSS) to people at risk of toxic drug harms and death amid the COVID-19 pandemic. We sought to assess the self-reported barriers to and outcomes of PSS among Indigenous people who sought or accessed a prescription. Methods: Cross-sectional and longitudinal surveys with up to 5 time points per participant over 3 months were used to collect data on health, health care, and systemic barriers. Outcome measures included health-related quality of life, psychosocial well-being, and behaviours related to unregulated substance use, COVID-19 protection, and criminalized income generation. Generalized estimating equations were used to assess the effects of time-varying PSS exposure on outcomes over the follow-up period. Results: Among the total sample (n=131), past negative experiences (64%), drug use stigma, (51%), mistrust (49%), negative reactions from health care providers (48%), and lack of privacy (46%) were reported in health care settings. Among the longitudinal cohort (n=102), there was no evidence of an effect of prescription receipt on change in any outcome over time or over the 12-week follow-up period, independent of prescription status, apart from COVID-19 protective behaviours, which showed a small increase over time (adj. β = 0.0090, 95% CI = 0.0043, 0.014). Conclusion: Limitations of the early implementation of PSS in BC included its medicalized delivery and lack of wraparound supports. Further work must be done to ensure the effectiveness, relevancy, and safety of prescribed safer supply for Indigenous people.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.057
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.306
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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