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Record W4416204755 · doi:10.1186/s40479-025-00322-2

An examination of the role of PTSD and childhood trauma on treatment outcomes for individuals with borderline personality disorder in dialectical behavior therapy

2025· article· en· W4416204755 on OpenAlexafffund
Katherine E. Christensen, Shelley McMain, Alexander L. Chapman, Janice R. Kuo

Bibliographic record

VenueBorderline Personality Disorder and Emotion Dysregulation · 2025
Typearticle
Languageen
FieldPsychology
TopicPersonality Disorders and Psychopathology
Canadian institutionsSimon Fraser UniversityUniversity of TorontoCentre for Addiction and Mental Health
FundersCanadian Institutes of Health Research
KeywordsBorderline personality disorderDialectical behavior therapyPersonalityAdverse Childhood ExperiencesPoison controlInjury preventionAnxiety disorder

Abstract

fetched live from OpenAlex

BACKGROUND: Borderline personality disorder (BPD) is a complex and severe mental health condition often accompanied by several co-occurring clinical problems. Posttraumatic stress disorder (PTSD) is one of the most common co-occurring disorders, with prevalence rates of PTSD reported to be between 25% and 58% among persons with BPD. The primary aim of the current study was to evaluate the association of a PTSD diagnosis and different forms of childhood trauma with changes in BPD severity, PTSD severity, and frequency of suicidal behaviors among suicidal individuals with BPD undergoing 12-months of standard dialectical behavior therapy (DBT). METHODS: This was a secondary data analysis that included individuals with BPD (N = 120) in the 12-month DBT condition. Participants completed measures of childhood abuse, PTSD severity, BPD severity, and frequency of suicidal behaviors at baseline as well as at 3, 6, 9, and 12 months. Generalized Estimating Equations (GEE) were used to examine both study hypotheses. RESULTS: Results suggested that the presence of PTSD did not predict reduced rates of reduction in BPD severity, PTSD severity, or frequency of suicidal behaviors. Results also revealed that higher severity of childhood sexual and emotional abuse was associated with quicker reductions in BPD severity, whereas higher severity of childhood physical abuse was associated with slower reductions. Similarly, higher severity of emotional abuse was associated with quicker reductions in PTSD severity, while higher severity of physical abuse was associated with slower reductions in this outcome. CONCLUSIONS: Standard DBT appears to be comparably effective for both individuals with BPD without PTSD and BPD + PTSD. The addition of a PTSD diagnosis did not significantly predict slower recovery among those with BPD + PTSD. In addition, different forms of childhood trauma significantly affect the trajectories of individual treatment. Our findings suggest that DBT interventions may be particularly beneficial for individuals with higher levels of emotional abuse. TRIAL REGISTRATION: NCT02387736. Registered February 20, 2015.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.237
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.327
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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