DO PARENTS AND PATIENTS WITH EARLY-ONSET SCOLIOSIS (EOS) SHARE THE SAME PERSPECTIVE ON HEALTH-RELATED QUALITY OF LIFE? A COMPARISON OF EOSQ-24 AND SRS-22 SCORES
Bibliographic record
Abstract
EOSQ-24 is validated in EOS patients aged 0-18 years and SRS-22 is validated in idiopathic scoliosis patients ≥10 years. EOSQ-24 is completed by the parent and SRS-22 is completed by the patient. A prior study comparing patient-reported outcome measures completed by older pediatric patients and their parents showed a low level of agreement. The aims of this study were (1) compare EOSQ-24 and SRS-22 scores completed at the same timepoint, and (2) compare EOSQ-24 and SRS-22 scores completed at subsequent timepoints, in patients aged 5-18 years with idiopathic or congenital scoliosis without developmental delay. This was a multicenter retrospective study. We identified pairs of EOSQ-24 and SRS-22 completed on the same day or within 6 months. Some patients had multiple pairs of surveys over time. EOSQ-24 and SRS-22 questions were matched using previously published methodology and domain scores for Pain, Function, Mental Health, and Satisfaction were compared. Patients with a change in treatment between completed surveys were excluded. Pearson Correlation test was used to compare EOSQ-24 and SRS-22 domain scores, with r>0.7 indicating a strong relationship. Four hundred and eleven pairs of EOSQ-24 and SRS-22 questionnaires were completed on the same day by 228 patients (Table 1). A strong correlation was found only for the Pain domain (r=0.77). Function, Mental Health, and Satisfaction domains had positive but not strong correlations (r= 0.58, r=0.50, r=0.41, respectively). Sub-analysis based on age also showed a strong correlation only for Pain (Table 2). There were 134 pairs of surveys with SRS-22 completed within 6 months after an EOSQ-24 by 76 patients (Table 1). All domains demonstrated a positive but not strong correlation, with Pain showing the highest correlation (r=0.64). EOSQ-24 and SRS-22 had a strong correlation only for the Pain domain when completed at the same timepoint. EOSQ-24 and SRS-22 completed within six months lacked a strong correlation for all domains. Our findings suggest that parents and older children with EOS may not share the same perspective on their health. Self-reported questionnaires may be more appropriate instruments to assess HRQoL in older, developmentally neurotypical patients with EOS. Future studies should further investigate how to compare proxy measures and self-reported outcome measures, as children with EOS develop cognitively with age and transition from parent-reported to self-reported questionnaires. For any figures or tables, please contact the authors directly.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".