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Record W4416282528 · doi:10.1139/gen-2024-0185

Karyotype analysis of the endangered tree frog <i>Nyctimantis pomba</i> (Anura: Hylidae: Lophyohylini) reveals differences from congeneric species

2025· article· en· W4416282528 on OpenAlexvenueno aff
Camila Moura Novaes, Eduarda Melo de Abreu Vieira, Gisele Amaro Teixeira, Denilce Meneses Lopes, Renato Neves Feio, Clodoaldo Lopes de Assis

Bibliographic record

VenueGenome · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicChromosomal and Genetic Variations
Canadian institutionsnot available
FundersConselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
KeywordsKaryotypeHeterochromatinPloidyCentromereCytogeneticsEndangered speciesSecondary constrictionMolecular cytogenetics

Abstract

fetched live from OpenAlex

Nyctimantis pomba is a critically endangered frog that has been the target of conservation programs, including captive breeding to prevent extinction. Data from different scientific fields, including cytogenetics, can be valuable for species conservation efforts. Here, we characterize the karyotype of N. pomba using conventional and molecular cytogenetics and discuss these data in light of the phylogeny of the genus. Nyctimantis pomba had a diploid chromosome number 2 n = 24 and exhibited a secondary constriction in one of the homologs of pair 9q, coincident with the rDNA sites. C-banding evidenced pericentromeric blocks on all chromosomes, and CMA 3 staining confirmed that these regions were GC-rich. AT-rich pericentromeric heterochromatin was observed in the long arm of pair 2. (TTAGGG) n probes labeled the telomeres of all chromosomes, with additional signals at the centromeric regions of some of them. (GA) n probes hybridized to the terminal regions of all chromosomes and pericentromeric regions of five pairs. These results showed that N. pomba differs from other karyotyped species by the presence of a nucleolar organizer region in pair 9, AT-rich pericentromeric heterochromatin in pair 2, and (TTAGGG) n signals in the centromeric regions. These variations represent distinct markers of N. pomba and indicate that cytogenetics may be a useful tool for detecting karyotypic differences in reintroduced populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.208
Teacher spread0.190 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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