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Medicinal Plant-Based Immunostimulants for Sustainable Shrimp Farming: From Bioactive Compounds to Reproductive Enhancement

2025· article· en· W4416318844 on OpenAlexaff
Nader N. Hassona, Ahmed A. Elshafey, Yun Li, Xilin Dai

Bibliographic record

VenueEgyptian Journal of Veterinary Science · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicInvertebrate Immune Response Mechanisms
Canadian institutionsMinistry of Agriculture
Fundersnot available
KeywordsShrimpHormoneEyestalkEndocrine systemFishingMedicinal plants

Abstract

fetched live from OpenAlex

The expansion of intensive shrimp aquaculture, driven by global food demand, is challenged by disease outbreaks and reliance on unsustainable practices like eyestalk ablation to induce reproduction in broodstock. This review explores the potential of medicinal plant-based immunostimulants as a sustainable alternative, with a specific focus on enhancing the reproductive performance of the Pacific white shrimp, Penaeus vannamei. We detail the complex endocrine regulation of crustacean reproduction, highlighting the roles of the X-organ-sinus gland complex, mandibular organ, and key hormones like methyl farnesoate. This foundation underscores the mechanistic drawbacks of eyestalk ablation, creating a compelling need for natural interventions. The paper then synthesizes evidence on how bioactive phytochemicals, including flavonoids, alkaloids, and sterols, can stimulate growth, immunity, and gonadal maturation. A thorough analysis of two promising plants, Melastoma malabathricum (Karamunting) and Cyperus spp., is presented. M. malabathricum, rich in lanosterol, acts as a precursor for steroid hormones, significantly accelerating ovarian development, increasing oocyte size, and elevating progesterone levels in P. vannamei. Conversely, Cyperus spp. contains methyl farnesoate, a crustacean juvenoid hormone analog, which promotes vitellogenesis, spermatogenesis, and molting, leading to advanced gonadal maturation stages and improved spawning performance. By compiling the molecular and endocrine evidence, this review positions these herbal extracts as effective, natural, and welfare-friendly alternatives to synthetic hormones and invasive techniques, offering a viable strategy to enhance reproductive efficiency and sustainability in shrimp hatcheries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.306
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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